Research on the role of herpes virus in the clinical course of a disease and the development of post-transplantation complications

07:35, 30 May, 2014
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On 3 June at 15:00 in an open meeting of the Medical Promotion Council of Rīga Stradiņš University that will take place in the Hippocrates lecture theatre (16 Dzirciema Street, Rīga), Alīna Sultanova will defend her doctoral thesis "Significance of Beta-Herpes Viruses (HHV-6, HHV-7) Infection under the Conditions of Immune Disorders".

Human herpes virus-6 (HHV-6) and herpes virus-7 (HHV-7) are widespread herpes viruses by which one gets infected in infancy and viruses survive throughout one’s life.

The aim of the thesis was to determine the role of the infection of beta-herpes viruses in clinical course of the disease and in the development of post-transplantation complications.

The results showed that the infection frequency and activity of HHV-6 and HHV-7 are different within three groups of patients with immune system disorders caused by different reasons, also differences in responses of immune system and changes in immunity were found.

When comparing the three groups of patients included in the research, it was concluded that patients who have had kidney transplantation and who have received a specific treatment had a weakened immune system and higher risk of beta-herpes virus activation, causing a variety of complications.