Microbiology

Study Course Description

Course Description Statuss:Approved

Course Description Version:6.00

Study Course Accepted:24.08.2022 10:45:49

Study Course Information
Course Code:		BUMK_049		LQF level:		Level 7
Credit Points:		4.00		ECTS:		6.00
Branch of Science:		Clinical Medicine; Microbiology and Virology		Target Audience:		Pharmacy
Study Course Supervisor
Course Supervisor:		Ingus Skadiņš
Study Course Implementer
Structural Unit:		Department of Biology and Microbiology
The Head of Structural Unit:
Contacts:		Riga, 16 Dzirciema Street, bmkrsu[pnkts]lv, +371 67061584
Study Course Planning
Full-Time - Semester No.1
Lectures (count)		5	Lecture Length (academic hours)		2	Total Contact Hours of Lectures		10
Classes (count)		11	Class Length (academic hours)		2	Total Contact Hours of Classes		22
Total Contact Hours								32
Full-Time - Semester No.2
Lectures (count)		5	Lecture Length (academic hours)		2	Total Contact Hours of Lectures		10
Classes (count)		11	Class Length (academic hours)		2	Total Contact Hours of Classes		22
Total Contact Hours								32
Study course description
Preliminary Knowledge:
In biology, anatomy, histology, biochemistry.
Objective:
To acquire knowledge about the spread, principles of classification, morphology, characteristics, methods for cultivation and identification of micro-organisms, fungi and viruses.
Topic Layout (Full-Time)
No.	Topic			Type of Implementation		Number	Venue
1	Introduction to microbiology. History of microbiology. Classification of micro-organisms. Morphology of bacteria. Atypical bacteria. Viruses. Fungi. Metabolism in bacteria. Human and environmental microflora. Factors affecting micro-organisms. Antibiotic substances. Resistance of micro-organisms to antibiotics.			Lectures		1.00	E-Studies platform
				Classes		1.00	auditorium
2	Microscopic examination methods. Simple and differential staining methods. Microscopy technique. Culture media. Plating technique. Investigation of air microflora. Determination of human microflora. Plating to determine the microflora of dosage forms.			Classes		2.00	laboratory
3	Medicinal plants and microflora of finished dosage forms. Phytopathogenic microbes. Plating of microflora of air, human body and dosage forms and analysis of the results thereof.			Lectures		1.00	E-Studies platform
				Classes		2.00	laboratory
4	Infection and immunity. Non-specific resistance factors: general, cellular, humoral. Specific immunity. Antigens and antibodies. Immunocompetent cells. Immune response. Hypersensitivity.			Lectures		1.00	E-Studies platform
				Classes		2.00	laboratory
5	Effect of physical, chemical and biological factors on micro-organisms. Sterilisation. Disinfection. Antibiotics, groups and mechanisms of action thereof. Development of resistance to antibiotic substances. Determining the susceptibility of micro-organisms to antibiotic substances.			Lectures		1.00	E-Studies platform
				Classes		3.00	laboratory
6	Principles of microbiological and serological diagnostics of infectious diseases. Immune serums. Diagnostic kits. Types of agglutination reactions. Reactions with marked Ag and AV, ELISA, immunofluorescence, PCR. Vaccines, types, principles of development and application thereof. Immune response and hypersensitivity.			Lectures		1.00	E-Studies platform
				Classes		2.00	laboratory
7	Wound infections and skin infections. The main group of bacterial, fungal and anaerobic infections, pathogenic cocci. Infections of the digestive tract. Intestinal bacteria, viral infections. Infections of the respiratory system. Bacterial and viral infections. Transmissible (blood) infections. Hepatitis viruses. HIV/AIDS. Neurotropic viruses.			Lectures		2.00	E-Studies platform
				Classes		3.00	laboratory
8	Properties of E.coli and salmonella, staphylococci and streptococci (group A and S.pneumoniae), meningococci and gonococci, pathogenicity factors, pathogenesis, prevention. Principles of microbiological diagnosis.			Lectures		1.00	E-Studies platform
				Classes		3.00	laboratory
9	Tuberculosis – agents, properties thereof, mechanisms of pathogenesis, principles of microbiological diagnosis, prevention. Spirochetoses (syphilis, Lyme disease), chlamydioses – agents, pathogenesis, microbiological diagnosis. Infections caused by pathogenic fungi (dermatophytes and Candida albicans) and diagnostic principles thereof.			Lectures		1.00	E-Studies platform
				Classes		2.00	laboratory
10	Agents of respiratory viral infections (influenza, parainfluenza, epidemic parotitis, measles, rubella) – pathogenesis of infections, diagnostic principles and specific prevention. Pathogenesis, diagnostic principles and specific prevention of adenovirus and herpesvirus infections. Agents of enteroviruses (rotavirus, norovirus) and hepatitis (A, B, C, D), pathogenesis of infections, diagnostic principles, prevention. Pathogenesis of neurotropic virus (tick-borne encephalitis) infections.			Lectures		1.00	E-Studies platform
				Classes		2.00	laboratory
Assessment
Unaided Work:
Students will independently prepare presentations for seminars on the immune response and hypersensitivity reactions, current agents of infectious diseases.
Assessment Criteria:
• regular attendance of classes, active participation in practical classes; • successful completion of weekly tests and semester colloquia; • assessment of independent learning; • cumulative exam at the end of the study course, fulfilling all criteria. Detailed information in e-studies. It is possible to decline the cumulative assessment and take the exam. The exam consists of four open-ended questions.
Final Examination (Full-Time):		Exam (Written)
Final Examination (Part-Time):
Learning Outcomes
Knowledge:		After completing the study course, students will be able to describe micro-organisms and the most relevant human parasites, describe their prevalence in the environment, understand and explain their pathogenicity and role in the origin of infectious diseases and interaction processes with macro-organisms.
Skills:		As a result of completing the study course, students will be able: • to investigate finished dosage forms; • to apply disinfection and sterilisation methods in the production process of pharmaceutical preparations; • to evaluate the aetiology of illnesses, sources of infection, transmission routes, pathogenesis, epidemiological hazard, prevention.
Competencies:		By combining theoretical knowledge with practical skills, students will have the opportunity to apply them in the form of a unified integrative understanding of the importance of bacterial and viral pathogenicity factors in the aetiology of the disease, and will be able to apply them to the mechanisms of pathogenesis and interaction with the host organism.
Bibliography
No.	Reference
Required Reading
1	Jawetz, Melnick, & Adelberg's Medical Microbiology. 27th ed., 2016.
2	P. Murray, et al. Medical Microbiology. 8th ed. 2021.
Additional Reading
1	Review of Medical Microbiology and Immunology. 17th ed., 2021
2	Aija Žileviča, Ivars Mazjānis – Medicīnas mikrobioloģija. Vispārīgā mikrobioloģija un infekcijas imunoloģija. Latvijas Universitātes akadēmiskais apgāds; 2014
3	Ārvalstu studentiem/For international students
4	Review of Medical Microbiology and Immunology. 17th ed., 2021
Other Information Sources
1	http://estudijas. rsu.lv.