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Clinical Pharmacy
Study Course Description
Course Description Statuss:Approved
Course Description Version:13.00
Study Course Accepted:21.06.2023 15:23:35
| Study Course Information | |||||||||
| Course Code: | FKK_018 | LQF level: | Level 7 | ||||||
| Credit Points: | 2.00 | ECTS: | 3.00 | ||||||
| Branch of Science: | Basic Sciences of Medicine, including Pharmacy; Clinical Pharmacy | Target Audience: | Pharmacy | ||||||
| Study Course Supervisor | |||||||||
| Course Supervisor: | Dace Bandere | ||||||||
| Study Course Implementer | |||||||||
| Structural Unit: | Department of Pharmaceutical Chemistry | ||||||||
| The Head of Structural Unit: | |||||||||
| Contacts: | Riga, 16 Dzirciema Street, Block A 5th floor, Room No. 502, farmkk rsu[pnkts]lv, +371 67061544 | ||||||||
| Study Course Planning | |||||||||
| Full-Time - Semester No.1 | |||||||||
| Lectures (count) | 10 | Lecture Length (academic hours) | 2 | Total Contact Hours of Lectures | 20 | ||||
| Classes (count) | 6 | Class Length (academic hours) | 2 | Total Contact Hours of Classes | 12 | ||||
| Total Contact Hours | 32 | ||||||||
| Study course description | |||||||||
| Preliminary Knowledge: | Pharmaceutical and medical chemistry, physiology, pharmacology. | ||||||||
| Objective: | To introduce pharmacy students to the concept of clinical pharmacy, basic principles of pharmacokinetics and their application in clinical practice. To promote understanding of various drug pharmacotherapy options. To analyze the guidelines and actualities of hospital and clinical pharmacy in Latvia and the world. | ||||||||
| Topic Layout (Full-Time) | |||||||||
| No. | Topic | Type of Implementation | Number | Venue | |||||
| 1 | Hospital pharmacy. Clinical pharmacy. Clinical pharmacokinetics and pharmacodynamics. | Lectures | 2.00 | laboratory | |||||
| 2 | Drug absorption, distribution, metabolism, elimination. | Lectures | 2.00 | laboratory | |||||
| 3 | Linear and non-linear pharmacokinetics. Drug interactions and side effects. Drug metabolism. | Lectures | 2.00 | laboratory | |||||
| 4 | Drugs for pediatric and geriatric population. Drugs and kidney failure. | Lectures | 2.00 | laboratory | |||||
| 5 | Pharmacokinetics of antibiotics. Individual drug therapy. | Lectures | 2.00 | laboratory | |||||
| 6 | Cardiological drugs – Digoxin, Lidocaine, Procainamide, Quinidine. Case study. Pharmacotherapy for chronic diseases and monitoring methods for safe and effective therapy. Personalised medicine from the perspective of a clinical pharmacist. | Classes | 2.00 | laboratory | |||||
| 7 | Individual therapy. Antiepileptics – Phenytoin, Carbamazepine, Valproates, Phenobarbital, Ethosuximide. Theophylline, Lithium, Ciclosporin, Tacrolimus. Dosage calculations. | Classes | 2.00 | laboratory | |||||
| 8 | The role of the clinical pharmacist in the hospital. | Classes | 2.00 | laboratory | |||||
| Assessment | |||||||||
| Unaided Work: | Individual and team work. Presentation of a report on pharmacokinetic processes. Analysis of pharmacotherapy situations and case situations. Completion of study course evaluation questionnaires. | ||||||||
| Assessment Criteria: | Case study analysis. Individual work – analysis of pharmacotherapy situations. Literature data analysis 50% and situation analysis 50% | ||||||||
| Final Examination (Full-Time): | Exam (Oral) | ||||||||
| Final Examination (Part-Time): | |||||||||
| Learning Outcomes | |||||||||
| Knowledge: | After successful acquisition of the course the students will be able to: • describe and explain pharmacokinetic and pharmacodynamic mechanisms; • describe and explain drug absorption, distribution, metabolism and excretion; • describe population needs as regards to medicines, ways of administration, patterns of use and drug effects on the patients; • identify and describe patient-specific data to improve pharmaceutical care. | ||||||||
| Skills: | After successful completion of the course the students will be able to assess and use pharmacokinetic parameters to choose the efficient therapy. | ||||||||
| Competencies: | After successfully completing the study course, the student will be able to evaluate the peculiarities of the use of various drugs, will be able to use the acquired knowledge about the diverse pharmacokinetic processes and mechanisms to make competent conclusions about individual pharmacotherapy. | ||||||||
| Bibliography | |||||||||
| No. | Reference | ||||||||
| Required Reading | |||||||||
| 1 | Whittlesea, C., Hodson, K. Clinical Pharmacy and Therapeutics. 6th edition. Elsevier, 2019. RSU:Informācijas centrs | ||||||||
| 2 | Oxford handbook of clinical pharmacy. Oxford, 2017. RSU:Brīvpieejas abonements RSU:Informācijas centrs | ||||||||
| Additional Reading | |||||||||
| 1 | Solverman, Richard B. The organic chemistry of drug design and drug action. 2014. RSU:Informācijas centrs | ||||||||
| 2 | Applied Biopharmaceutics & Pharmacokinetics. Editors Shargel L., Wu-Pong S., Yu A. B. C. 5th edition. McGraw Hill AccessPharmacy, 2022. -892 p. | ||||||||
| 3 | Applications of Pharmacokinetic Principles in Drug Development. Editor Krishna R. Kluwer Academic Plenum Publishers, 2004. -556 p. | ||||||||
| 4 | Bauer, L.A. Applied Clinical Pharmacokinetics. McGraw Hill AccessPharmacy, 2014. -759 p. | ||||||||
| 5 | Drug Benefits and Risks. Editors Boxtel C. J., Santoso B., Edeards I. R. John Wiley & Sons, EBSCOhost Ebook Academic Collection, 2008. | ||||||||
| 6 | Drug Prescribing in Renal Failure. Editors Aronoff, G. R., Berns, J. S., Brier, M. E., et.al. 4th edition. American College of Physicians, 1999. -176 p. | ||||||||
| 7 | Rowland and Tozer's Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications. 5th edition, 2020. | ||||||||
