Pathology

Study Course Description

Course Description Statuss:Approved

Course Description Version:4.00

Study Course Accepted:20.01.2023 10:10:58

Study Course Information
Course Code:		PAK_021		LQF level:		Level 7
Credit Points:		4.00		ECTS:		6.00
Branch of Science:		Clinical Medicine; Pathology		Target Audience:		Pharmacy
Study Course Supervisor
Course Supervisor:		Ilze Štrumfa
Study Course Implementer
Structural Unit:		Department of Pathology
The Head of Structural Unit:
Contacts:		RSU, 9a Kuldigas Street, LV-1007, pakrsu[pnkts]lv, +371 67815096
Study Course Planning
Full-Time - Semester No.1
Lectures (count)		6	Lecture Length (academic hours)		2	Total Contact Hours of Lectures		12
Classes (count)		10	Class Length (academic hours)		2	Total Contact Hours of Classes		20
Total Contact Hours								32
Full-Time - Semester No.2
Lectures (count)		0	Lecture Length (academic hours)		0	Total Contact Hours of Lectures		0
Classes (count)		16	Class Length (academic hours)		2	Total Contact Hours of Classes		32
Total Contact Hours								32
Part-Time - Semester No.1
Lectures (count)		8	Lecture Length (academic hours)		4	Total Contact Hours of Lectures		32
Classes (count)		8	Class Length (academic hours)		4	Total Contact Hours of Classes		32
Total Contact Hours								64
Study course description
Preliminary Knowledge:
Cell biology, human anatomy and physiology, biochemistry.
Objective:
1. To provide studies in pathology, including morphological and functional manifestations of diseases, their pathogenesis. This aspect of the programme should provide theoretical grounds for the mastering of clinical and speciality-related courses preparing a comprehensively educated pharmacy specialist. The pathology programme should include, in an integrated way, the progress of local and general pathological processes, developing a uniform idea of the morphological and functional components of disease pathogenesis for the student; 2. To provide a practical overview of pathology as a diagnostic branch of medicine and a component of medical research at the level appropriate for pharmacy specialist’s work.
Topic Layout (Full-Time)
No.	Topic			Type of Implementation		Number	Venue
1	The most common general pathological processes: inflammation, circulatory disorders and hypoxia.			Lectures		1.00	auditorium
2	Insight into tumour development, pathogenetic principles of diagnosis and therapy thereof.			Lectures		1.00	auditorium
3	Insight into renal pathology.			Lectures		1.00	auditorium
4	Insight into the pathogenesis of the most common cardiovascular diseases.			Lectures		1.00	auditorium
5	Insight into gastrointestinal tract and liver pathology.			Lectures		2.00	auditorium
8	Concept of a disease as a process, diagnosis, pathogenesis, complications and risk factors. Cell damage and compensatory adaptation processes.			Classes		1.00	auditorium
9	Peripheral circulation disorders. Hypoxia.			Classes		1.00	auditorium
10	Nature and manifestations of acute and chronic inflammation. The concept of autoimmune diseases.			Classes		1.00	auditorium
11	Systemic and laboratory manifestations of inflammation. Fever.			Classes		1.00	auditorium
13	Characterisation of the most common and relevant tumours in society.			Classes		1.00	auditorium
14	Acid-alkaline imbalances. Hypohydration. Hyperhydration. Electrolyte exchange disorders.			Classes		1.00	auditorium
15	Acute renal failure. Chronic kidney disease.			Classes		1.00	auditorium
16	Atherosclerosis. Coronary heart disease. Arterial hypertension and other cardiovascular diseases.			Classes		1.00	auditorium
17	Colloquium.			Classes		2.00	computer room
18	Diseases of the upper gastrointestinal tract. The concept of malnutrition and vomiting.			Classes		1.00	auditorium
19	Focal and diffuse liver diseases.			Classes		1.00	auditorium
20	Diseases of the lower gastrointestinal tract. The concept of malabsorption and diarrhoea.			Classes		1.00	auditorium
21	Liver cirrhosis. Portal hypertension. Liver failure. Jaundice.			Classes		2.00	auditorium
22	Gallbladder and pancreatic diseases.			Classes		1.00	auditorium
23	Haematological pathology I: anaemias.			Classes		1.00	auditorium
24	Haematological pathology II: leukocyte reactions and coagulation disorders.			Classes		1.00	auditorium
25	Lung diseases.			Classes		1.00	auditorium
26	Diffuse bone diseases. Calcium and vitamin D metabolism disorders. Insight into central nervous system (CNS) pathology.			Classes		2.00	auditorium
27	Diabetes mellitus and complications thereof.			Classes		1.00	auditorium
28	Other endocrine pathologies			Classes		2.00	auditorium
29	Colloquium			Classes		2.00	auditorium
Topic Layout (Part-Time)
No.	Topic			Type of Implementation		Number	Venue
30	The concept of disease as a process, its aetiology and pathogenesis. Concept of cell damage, pathogenesis thereof and related medical terminology.			Lectures		1.00	auditorium
31	Peripheral circulation disorders: nature, pathogenesis, terminology. The concept of hypoxia.			Classes		1.00	auditorium
32	Inflammation. Fever.			Classes		1.00	auditorium
33	Insight into water and electrolyte imbalances. Insight into acid-alkaline imbalances.			Lectures		1.00	auditorium
34	Renal pathology.			Lectures		1.00	auditorium
35	Insight into cardiovascular pathology. Atherosclerosis and the organ damage caused by it. The concept of coronary heart disease, myocardial infarction, and stenocardia.			Classes		1.00	auditorium
36	Diabetes mellitus and complications thereof.			Classes		1.00	auditorium
37	Tumours: an insight into the problem. Clinically relevant classifications (TNM, WHO).			Lectures		1.00	auditorium
38	Insight into liver, gallbladder and pancreatic pathology: focal and diffuse liver diseases. Liver cirrhosis. Jaundice. Gallstone disease and complications thereof. Acute and chronic pancreatitis. Hepatobiliopancreatic tumours.			Lectures		1.00	auditorium
39	Insights into the pathology of the gastrointestinal tract.			Classes		1.00	auditorium
40	Insight into the pathogenesis of the most common lung diseases.			Classes		1.00	auditorium
41	Tissue and organ damage caused by medicines.			Lectures		1.00	auditorium
42	Pathology of the haematopoietic system: anaemia. The concept of polycythaemia. Leukocyte reactions. Blood clotting disorders.			Classes		1.00	auditorium
43	Pathology of the thyroid gland, parathyroid and adrenal glands.			Lectures		1.00	auditorium
44	Bone pathology. Calcium metabolism disorders.			Classes		1.00	auditorium
45	Insight into central nervous system (CNS) pathology: concept of vascular, inflammatory, degenerative and neoplastic CNS diseases.			Lectures		1.00	auditorium
Assessment
Unaided Work:
Learning the study material according to the topics specified in the e-studies and the posted study materials.
Assessment Criteria:
Examination of the study course: During the study course, lecturers test knowledge using short test works (multiple-choice test or other short form of test as per teaching staff instructions). During the studies, students have colloquia with theoretical questions in the form of a multiple choice test and/or clinical text assignments reflecting the pathologies discussed during studies. At the end of the study course, in accordance with the planning of the respective study programme students take a written or electronic examination in the form of a multiple-choice test. In accordance with the RSU Academic Regulations (approved at the RSU Senate meeting of 21 April 2020; minutes No.2-1/4/2020), Paragraph 2.16, the final mark of the study course consists of the cumulative assessment (50%) and real knowledge obtained by the student (50%) in accordance with the result of the final course examination. The assessment of all test works, incl. in percentage and with grades, takes place in accordance with the current version of the Academic Regulations I of Rīga Stradiņš University.
Final Examination (Full-Time):		Exam (Written)
Final Examination (Part-Time):		Exam (Written)
Learning Outcomes
Knowledge:		As a result of completing the study course, the student will know and will be able to explain in a reasoned way the nature of individual diseases and general pathological processes; pathogenesis and its manifestations in clinical processes, imaging and laboratory examinations; causes and risk factors; potential complications and consequences, as well as outcomes, as far as the scope of the study course allows.
Skills:		As far as the scope of the study course allows, the student will learn, through clinical assignments, to identify the most common pathologies, reasoned evaluation of the pathogenesis of the diseases referred to in the thematic plan of the course, associate it with clinical manifestations of diseases and diagnostic basis, and to act practically organising the necessary laboratory examinations, interpreting and critically analysing the results thereof in relation to the overall picture of the disease. Knowledge and understanding of the pathogenesis of diseases will serve as a basis for developing the skills to carry out scientific research in the pharmaceutical field.
Competencies:		The student will be competent to formulate, differentiate, analyse and substantiate the course of pathological processes.
Bibliography
No.	Reference
Required Reading
1	RSU Patoloģijas katedras docētāju sagatavotie e-studiju lekciju materiāli, PAK_021
2	RSU Patoloģijas katedras docētāju sagatavotie e-studiju nodarbību materiāli, PAK_021
3	Robbins Basic Pathology, 7th ed.. Kumar V, Cotran RS, Robbins SL. Saunders, Philadelphia, 2018, 873 lpp.
4	Robbins and Cotran Pathological Basis of Disease, 8th ed. Kumar V, Abbas AK, Fausto N, Aster J. Elsevier, 2020.
5	Ārvalstu studentiem/For international students
6	Robbins Basic Pathology, 7th ed.. Kumar V, Cotran RS, Robbins SL. Saunders, Philadelphia, 2018, 873 lpp.
7	Robbins and Cotran Pathological Basis of Disease, 8th ed. Kumar V, Abbas AK, Fausto N, Aster J. Elsevier, 2020.
Additional Reading
1	Klīniskā medicīna, prof. A.Lejnieka redakcijā. Rīga : Medicīnas apgāds, 2010-2012