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About Study Course

Credit points / ECTS:4 / 6
Course supervisor: Rudīte Koka
Study type:Full time
Course level:Bachelor
Target audience:Dentistry
Language:English, Latvian
Branch of science:Biology; Molecular Biology

Objective

To make understanding about molecular processes in cell, linkage between cell function and provision of homeostasis in human body, as well as understanding about principles of human genome structure and role of disturbances in genome in etiology of genetic pathologies, to develop skills of students in work with methods of molecular biology, to help to understand the use of theoretical knowledge in medical practice, to help to understand role of science in medical development and use of scientific opinion in practice of a medical doctor.

Prerequisites

Knowledge of biology acquired within the framework of general secondary education.

Learning outcomes

Knowledge

• Students analyse the conformity of eukaryotic cell structure with its functions;
• justify interrelation of the cell structure and the role of abnormal function in human pathology;
• compare processes in mitosis and meiosis;
• know the main conformities of genetics;
• evaluate the role of Mendel's experiments in the development of genetics;
• compare the results of monohybrid, dihybrid, polyhybrid and analytic crosses;
• explain types of interaction of allelic and non-allelic genes and impact of interaction on the manifestation of features in phenotype;
• analyse the interconnection between genes;
• know the primary and secondary structure of nucleic acids;
• explain the replication, transcription, translation of DNA and regulation of gene expression;
• recognise chromosomal pathologies, analyse possible mechanisms of origin and consequences;
• distinguish factors of disarrangement of gene balance in population, know the types of selection and describe the selection in human population;
• explain the application of genetic cognitions in medical practice;
• justify the manifestations of mutations of development genes in early stages of onthogenesis;
• explain the impact of development genes on the formation of the human body;
• defend the opinion while analysing particular situations regarding inheriting of human features;
• apply conceptions and terms discussed during classes.

Skills

Upon successful completion of the course students will be able to:
• use light microscope in order to identify specific structures of eukaryote cell, metaphase chromosomes, polytene chromosomes; explain the connection of structure and functions;
• portray the phase of mitosis and meiosis graphically and explain the on-going processes;
• create the schemes of oogenesis and spermogenesis, compile and analyse family medical tree; present the etiology of diseases resulting from multifactorial inheritance, possible causes, single out and prove DNA, classify types of changeability and mutation;
• discuss about the creation mechanisms of genes, chromosomes, genome mutations; solve the tasks regarding genetics and molecular biology.

Competence

Students will be able to analyse situations in medical pathology, genetics, evaluate scientific achievements and the role of genetics in dental practice.

Study course planning

Planning period:Year 2020, Autumn semester
Study programmeStudy semesterProgram levelStudy course categoryLecturersSchedule
Dentistry1Master’sRequiredRudīte Koka
Dentistry1Master’sRequiredMiki Nakazawa-Miklaševiča, Aija Strode
Dentistry2Master’sRequiredMiki Nakazawa-Miklaševiča
Planning period:Year 2021, Spring semester
Study programmeStudy semesterProgram levelStudy course categoryLecturersSchedule
Dentistry2Master’sRequiredRudīte Koka
Dentistry2Master’sRequiredMiki Nakazawa-Miklaševiča
Dentistry1Master’sRequiredMiki Nakazawa-Miklaševiča, Aija Strode