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Supervisor
Ludmila Vīksna

Study Course Description

Course Description Statuss:Approved
Course Description Version:4.00
Study Course Accepted:30.08.2019
Study Course Information
Course Code:IUDK_016LQF level:Level 6
Credit Points:8.00ECTS:12.00
Branch of Science:Medicine; Infectious DiseasesTarget Audience:Medicine
Study Course Supervisor
Course Supervisor:Ludmila Vīksna
Study Course Implementer
Structural Unit:
The Head of Structural Unit:Ludmila Vīksna
Contacts:Rīga, Linezera iela 3, idkatrsu[pnkts]lv, idkatrsu[pnkts]lv, +371 67014777
Study Course Planning
Full-Time - 1. Semester No.
Lectures (number)15Lecture Length (academic hours)2Total Contact Hours of Lectures30
Classes (number)10Class Length (academic hours)5Total Contact Hours of Classes50
Total Contact Hours80
Lectures (number)5Lecture Length (academic hours)2Total Contact Hours of Lectures10
Classes (number)14Class Length (academic hours)5Total Contact Hours of Classes70
Total Contact Hours80
Study course description
Preliminary Knowledge:
Anatomy, biochemistry, biology, parasitology, pathologic physiology, microbiology, immunology, pharmacology, propaedeutic, internal diseases.
Objective:
To provide theoretical and practical knowledge of developmental mechanisms and aetiology of infectious diseases in the human body in correlation with clinical symptoms and possibility of treatment and specific or etiological therapy, as well as of prophylactic methods against infectious diseases, control of spread of infectious diseases, impact on public health and quality of life of each individual.
Topic Layout (Full-Time)
No.TopicType of ImplementationNumberVenue
1Communicable diseases in a global context – current situation and expectations in future. Infectology in the overall spectrum of diseases. Theoretical and practical basics of infectology, infection process.Lectures1.00auditorium
2The epidemiology of infectious diseases, epidemic process. The epidemiological investigations, surveillance and control of communicable diseases.Lectures1.00auditorium
3Diagnostic principles in Infectology: epidemiological, clinical, laboratory – specific and non-specific.Lectures1.00auditorium
4Principles of treatment in Infectology – specific, etiological, pathogenic and symptomatic therapy, application of principles.Lectures1.00auditorium
5Specific laboratory tests/investigations in modern Infectology – selection principles, methods, interpretation.Lectures1.00auditorium
6Causes of hospital-acquired infections/ healthcare-associated infections: manifestations and causative agents. Socio-medical significance. Prophylaxis and treatment.Lectures1.00auditorium
7Blood-borne infectious diseases – terminology, epidemiology, etiology, prophylaxis. Importance in individual and public health.Lectures1.00auditorium
8Fecal-orally transmitted infections – definition, aetiology, epidemiology (viral, bacterial, parasitic). Principles of diagnostics and treatment, prophylaxis. Importance in the life of individuals and the life of society in general.Lectures1.00auditorium
9Air-borne infections – definition, etiology, epidemiology, principles of diagnostics and treatment of viral, bacterial and fungal infections, prophylaxis/ preventive measures. Social significance.Lectures1.00auditorium
10Lower respiratory tract infections: acute bronchitis, bronchiolitis and pneumonia. Epidemiology, aetiology, clinical manifestation, diagnostic approach, and principles of treatment.Lectures1.00auditorium
11Tuberculosis: epidemiology, aetiology, pathogenesis, diagnostic microbiology and principles of treatment.Lectures1.00auditorium
12Neuroinfections – definitions, aetiology, epidemiology, diagnostic and treatment principles, prevention options. Social significance.Lectures1.00auditorium
13Diagnosis and differential diagnosis of infectious diseases characterized by pathologies in pharynx.Lectures1.00auditorium
14Slow and congenital infections: definitions, etiology, clinical manifestations, diagnostic principles, prognosis.Lectures1.00auditorium
15Parasitic infections – definition, etiology, classification, principles of treatment and prevention. Social significance.Lectures1.00auditorium
16Bioterrorism – definitions, terminology, classification. Objectives of health-care in bioterrorism-related situations. Regulatory basis for action in case of bioterrorism threats.Lectures1.00auditorium
17Protozoa-induced diseases: terminology, classification, etiology, epidemiology.Lectures1.00auditorium
18Range of infectious diseases in travelers, immigrants, refugees, areas plagued by war. Diagnostics, principles of health care and prevention.Lectures1.00auditorium
19Food and environment as source of infectious diseases – latest trends.Lectures1.00auditorium
20Pediatric infections in adults – diagnostics, peculiarities of clinical manifestation, prognosis and prophylaxis.Lectures1.00auditorium
21Organizational principles of Infectios diseases hospital. Rules of transportation and hospitalization of patients with infectious diseases. Medical device reprocessing principles (cleaning, disinfectiopn, sterilization, process control, regulatory documents).Classes1.00clinical base
22Practical aspects of specific laboratory diagnostics of infectious diseases and evaluationor assessment of obtained results.Classes1.00clinical base
23Acute viral respiratory diseases – influenza, adenovirus infection, rhino-syncytial infection, coronavirus infection, etc. Examination of patients, investigation and verification of diagnosis. Treatment tactics.Classes1.00clinical base
24Acute bacterial respiratory diseases – pneumococcal infection, legionellosis, pertussis, diphtheria and other infections caused by mycoplasma and chlamydia. Examination of patients, investigation and verification of diagnosis. Treatment tactics.Classes1.00clinical base
25Acute viral intestinal infections – diseases caused by rotavirus, norovirus, coronavirus. Clinical manifestations, principles of diagnostics and treatment. Prophylaxis.Classes1.00clinical base
26Acute bacterial intestinal infections – diseases caused by Salmonella (incl. S.typhi un S.paratyphi), Shigella, E.Coli, Cl.difficile, Campylobacter, Yersinia, V.cholerae and other microorganisms. Food or foodborne toxicoinfections, incl. botulism. Principles of diagnostics and treatment. Prophylaxis.Classes1.00clinical base
27Examination of patients with suspected tuberculosis Approach to tuberculosis diagnosis. Tuberculosis infection control. Postprimary pulmonary tuberculosis.Classes1.00clinical base
28Tuberculosis in children. Tuberculosis peculiarities of the elderly and immunocompromised patients. Management of most common complications of pulmonary tuberculosis.Classes1.00clinical base
29Process of HIV infection during – acute retroviral syndrome, chronic form, clinical manifestations diagnostics, differential diagnosis, principles of treatment.Classes1.00clinical base
30AIDS opportunistic infectious diseases. Diagnostics, therapy, prophylaxis. Patient care.Classes1.00clinical base
31Algorithm for diagnistics of acute infectious diseases (viral, bacterial) characterized by jaundice. Clinical manifestations of acute liver cell failure (hepatocyte insufficiency), biochemical markers, etiological and pathogenic treatment. Types of acute viral hepatitis (A, B, herpesvirus a.o.) – clinical differences depending on aetiology, clinical investigation/ examination, verification of diagnosis.Classes1.00clinical base
32Chronic viral hepatitis (B, C a.o.). Clinical manifestations, verification of diagnosis. Principles of treatment. Bacterial hepatitis – leptospirosis, typhoid fever a.o. Differential diagnosis. Final outcomes.Classes1.00clinical base
33Infections caused by Herpes viruses: typical clinical manifestations, differences, differential diagnosis, prevention and treatment options of pathologies caused by HHV1, HHV2, HHV3, HHV4, HHV5, HHV6, HHV7, HHV8.Classes1.00clinical base
34Parasitic infections: diseases caused by blood parasites; tropical diseases/ parasitoses typical for tropical areas. Preparation/ getting ready for a travel (special areas, specific groups of patients, specific immunoprophylaxis, etc.). Travel-related health problems after return. Rabies.Classes1.00clinical base
35The most essential human helmintoses – diseases caused by nematodes, cestodes, trematodes. Clinical syndromes, diagnosis, principles of treatment and prevention options. Nematodes, reported in Latvia less commonly. Characteristics of filariasis.Classes1.00clinical base
36Most common forms of extrapulmonary tuberculosis. Pleural manifestations of tuberculosis. Miliary tuberculosis.Classes1.00clinical base
37Viral neuroinfections – tick-borne encephalitis, meningitis caused by epidemic parotitis virus, enteroviruses (including polio virus), herpesviruses, lymphocytic choriomeningitis, West Nile fever, etc. Bacterial neuroinfections – pneumococcal, meningococcal, tuberculous – clinical manifestations, investigation, examination of patients, principles of diagnostics and treatment. Meningitis caused by protozoa and fungi.Classes1.00clinical base
38Lyme borreliosis, erlichiosis, Q fever, rickettsiosis a.o. – investigation, verification of diagnosis, treatment principles. Prophylaxis.Classes1.00clinical base
39Systemic and opportunistic mycoses – epidemiology, etiology, pathogenesis, pulmonary and extrapulmonary manifestations.Classes1.00clinical base
40Psitakosis and other zoonoses of the world.Classes1.00clinical base
41Life-threatening infections.Classes1.00clinical base
42Hemorrhagic fevers – definition, classification, etiologic groups, clinical manifestations, verification of diagnosis, principles of treatment. Currently topical exotic diseases – Ebola fever, Zika virus disease. Dengue fever.Classes1.00clinical base
43Adult vaccination: aims and objectives; indications and contraindications; practical aspects of vaccination. Immunoglobulins, serum. Malaria prevention. Tetanus. Traveler Diseases.Classes1.00clinical base
44Microbiological criteria for food and environmental objects and organisation of laboratory control.Classes1.00clinical base
Assessment
Unaided Work:
1. Preliminary preparation for each practical class (relevant topic); 2. Independent study report (the 7th semester); 3. Academic history of disease (the 8th semester) – a case report.
Assessment Criteria:
Independent work: 1. Independent study report: assessment criteria – compliance of the content of the report with the selected topic; design of the report; student’s individual input, contribution or work invested; level of student’s knowledge evaluated by the lecturer (responsible for the group) when discussing the individual study report with the student. 2. Academic history of a disease: assessment criteria – justification and arguments for final clinical diagnosis; student’s individual work with the patient; the compliance of content and form with methodological guidelines; assessment of the student’s knowledge and understanding about the clinical diagnosis of patient. Examination: Activity (involvement, participation) during practical classes, assessment of the independent study report, assessment of the academic history of the disease, final assessment of the acquired knowledge - results of the multiple-choice test, assessment of theoretical knowledge and practical knowledge (situation task).
Final Examination (Full-Time):Exam (Written)
Final Examination (Part-Time):
Learning Outcomes
Knowledge:Students will be able to describe and classify infectious diseases according to etiological factor, prevailing symptoms, type of spread, levels of disease severity, hazard to public health and each individual; to identify and describe specific, typical, pathogenetic and other symptoms; to explain the programme or plan of investigations and systematize the methods; to define and explain general principles of treatment; to define steps of health care plan for individual treatment/to relate steps of health care plan to individual treatment; to describe and comment on current principles of specific prophylaxis, applying them on public health level as well as to each individual patient.
Skills:The students will be able to develop an action plan for diagnosis and treatment of the disease of the patient; to implement the created plan based on collected anamnesis and data obtained from laboratory tests and other investigations; to evaluate data of physical examination of the patient; the students will be competent to integrate results of laboratory investigations in the design of disease diagnostics; to plan prevention activities in order to control the spread of disease.
Competencies:To apply basic knowledge and skills of reasoning, logics and public speaking in order to analyse situations in practical infectology, to discuss and explain personal viewpoint/opinion and constructively promote achievement of professional goals and specific tasks in order to provide individual and public health care; to communicate successfully with patients, their relatives and medical professionals as regards diagnostics, differential diagnosis, prevention and treatment of infectious diseases; to provide patient care in cooperation with patients, their relatives and medical experts, while respecting patients’ rights and norms of medical ethics; to study independently and use e-health medical resources for communication with other students and colleagues; to demonstrate and improve personal professional skills and develop oneself as a potential health care provider and promoter in the context of specific and non-specific prophylaxis of the infectious diseases.
Bibliography
No.Reference
1Bennett J.E., Dolin R.l., Blaser Mandell M. J., Douglas, and Bennett's Principles and Practice of Infectious Diseases (Eighth Edition), ISBN: 978-1-4557-4801-3
2Vīksna L. Infekcijas slimības. Rīga: Medicīnas apgāds; 2011.
3Maxine A. Papadakis, Stephen J. McPhee, Michael W. Rabow Lange Current Medical Diagnosis and Treatment 2018, 57th Edition; „Innere Medizin“ Gerd Herold and Associates
4Fred F. Ferri. Ferri's Clinical Advisor 2019, Elsevier.
5Zeltiņa I., Zavadska D, Grope I., Aldiņš P., Savrasova L., Grāmatniece A., Žilde A. Praktiskas rekomendācijas vakcinācijai veseliem pieaugušajiem un riska grupu indivīdiem Latvijā. Rīga. Slimību profilakses un kontroles centrs; 2019
6Cilvēka imūndeficīta vīrusa (HIV) infekcijas diagnostikas, ārstēšanas un profilakses klīniskās vadlīnijas. 2014
7Vīksna L. Vakcinācija: aktīvā specifiskā imūnprofilakse. Rīga: Nacionālais apgāds; 2008.
8Vīrushepatīta B diagnostikas un etitropās ārstēšanas vadlīnijas. 2011
9HIV/AIDS quidelines 2018
10EACS quidelines European AIDS clinical society
11Tuberkulozes klīniskās vadlīnijas. 2015.
12Madhukar Pai, Marcel A. Behr, David Dowdy, et.al. Tuberculosis. Nature reviews, Volume 2, 2016
13Garcia-Monco J.C. CNS infections. Clinical approach. Springer, 2018
14Vīksna L. Vīrushepatīts C: norise, ārstēšana, prognoze, profilakse. Rīga: Nacionālais apgāds; 2003.
15Danilāns A. Hroniskas aknu slimības. Rīga: Medicīnas apgāds; 2009.
16Zinčenko L, Krūmiņa A. Medicīniskā helmintoloģija. Rīga: Vītola izdevniecība; 2010.
17Bacon B R, et al, editors. Comprehensive Clinical Hepatology. 2nd ed. St Louis; London: Elsevier Mosby; 2010.
18Bartlett J G, Gallant J E, Pham P A. 2009-2010 Medical Management of HIV Infection. Johns Hopkins University School of Medicine; 2009.
19Cohen J, Opal S M, Powderly W G, editors. Infectious Diseases. 2 vol. 3rd ed. St. Louis, Mo.; London: Mosby; 2010.
20Wenzel R, Bearman G, Brewer T, Butzler J P. A Guide to Infection Control in the Hospital. 4th ed. Boston: International Society for Infectious Diseases. 2008.
21Goldman L., Schafer A. “Goldman-Cecil Medicine”, 25th Ed. Elsevier Inc. 2016
22"The Human Microbiota and Chronic Disease: Dysbiosis as a Cause of Human Pathology" (izdota 2016. gadā, izdevniecība "Wiley-Blackwell")
23CDC Yellow Book 2018: Health Information for International Travel, Oxford University Press, 704 lpp., 2017.
24Opportunistic Infection/HIV.gov
1Solomon T et al. Management of suspected viral encephalitis in adults-Association of British Neurologists and British Infection Association National Guidelines. 2012 Apr;64(4):347-73. doi: 10.1016/j.jinf.2011.11.014. Epub 2011 Nov 18.
2Baldwin, K. J., & Zunt, J. R. (2014). Evaluation and Treatment of Chronic Meningitis. The Neurohospitalist, 4(4), 185–195.
3EASL Recommendations on Treatment of Hepatitis C 2018. Journal of Hepatology
4EASL Clinical Practice Guidelines For The Management Of Patients With Decompensated Cirrhosis. Journal of Hepatology
5EASL Clinical Practice Guidelines On Hepatitis E Virus Infection
6EASL Clinical Practice Guidelines: Management Of Alcohol-Related Liver Disease
7EASL 2017 Clinical Practice Guidelines On The Management Of Hepatitis B Virus Infection
8Schlossberg D. Clinical Infectious Disease. Cambrige: Cambridge University Press; 2008.
9Peters W, Pasvol G. Atlas of Tropical Medicine and Parasitology. 6th ed. Philadelphia: Elsevier Mosby; 2007.
10Белопольский Ю А. Справочник по инфекционным болезням. Москва; 2009.
11Покровский В И, Пак С Г, Брико Н И, Данилкин Б К. Инфекционные болезни и эпидемиология. 2-e изд. Москва; 2009.
12Gilbert D N, et al. The Sanford Guide to Antimicrobial Therapy Sperryville; Antimicrobial Therapy; 2009.
13Brila A. Infekcijas slimību epidemioloģija. Rīga: Nacionālais apgāds; 2009.
14Sulis G., Centis R., Sotgiu G. et al. Recent developments in the diagnosis and management of tuberculosis. npj Primary Care Respiratory Medicine (2016) 26, 16078; doi:10.1038/npjpcrm.2016.78
15Foster G R, Goldin R D. Management of Chronic Viral Hepatitis. 2nd ed. London: Taylor & Francis; 2005.
16Dheda K., Gumbo T., Maartens G. et al. The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis. The Lancet Respiratory Medicine Commission.
17Feldman M, Friedman L S, Brandt L J. Sleisenger and Fordtran’s Gastrointestinal and Liver Disease: Review and Assessment. 2 vol. 9th edition. Edinburgh: Elsevier Sounders; 2010.
1https://accessmedicine.mhmedical.com
2https://www.clinicalkey.com
3http://site.ebrary.com/lib/rsub
4http://search.ebscohost.com/
5http://www.who.int/
6www.uptudate.com
7https://www.ean.org/ENCEPHALITIS-VIRAL-MENINGOENCEPHALITIS-…
8https://ecdc.europa.eu/sites/
9https://ecdc.europa.eu/en/news-events
10https://www.ncbi.nlm.nih.gov/pubmed/
11https://www.ncbi.nlm.nih.gov/books/
12https://emedicine.medscape.com/
13https://www.cdc.gov/
14http://www.antimicrobe.org/
15https://www-amboss-com.db.rsu.lv/row/campus/2018/rsu-activa…
16http://www.dynamed.com/
17http://www.merckmanuals.com/
18https://aricjournal.biomedcentral.com/articles/
19http://www.mayoclinic.org/diseases