Pharmaceutical analyses and technologies

No.	Analytical services	Planned execution time	Minimum price, EUR
1	Qualitative and quantitative analysis (potentiometric and KF titration, sulphated ash, etc.)	2–3 days	100
2	Impurity analysis in drug substances and raw materials (HPLC-UV/RI/FLD)	2–4 days	300
3	Impurity analysis in drug substances and raw materials (HPLC-MS/MS)	2–5 days	500
4	Solvent residues in drug substances (GC-FID, GC-HS/FID)	2–4 days	200
5	Trace metal analysis (ICP-MS/MS)	2–4 days	300
6	Morfological analysis of API's and excipients (microscopy, particle size distribution)	2–3 days	200
7	Dissolution testing (dissolution system, HPLC-UV/RI/FLD)	2–5 days	400
8	Analytical method development (HPLC-UV/RI/FLD, HPLC-MS/MS, GC-FID, GC-HS/FID, ICP-MS/MS)	1–2 weeks	2000
9	Forced degradation study (acids, basic, oxidative, temperature, temperature/humidity, photostability)	2–4 weeks	1500
10	Method validation (depends on the method) (HPLC-UV/RI/FLD, HPLC-MS/MS, GC-FID, GC-HS/FID, ICP-MS/MS)	2–4 weeks	8000
11	Compatibility testing (HPLC-UV/RI/FLD, HPLC-MS/MS, DSC, pXRD, FTIR)	1–2 weeks	1500
12	Pre-stability study (1 batch)	6–12 months	10000
13	Rheological analysis	2–4 days	300
	Technological services (analytical chemistry services not included)
14	Micronization of substances	1–2 days	500
15	Tableting	2–4 days	500
16	Capsuling in hard capsules (HPMC)	2–4 days	500
17	Roller compaction	2–4 days	500
18	Wet granulation	2–3 days	500
19	Hot-melt extrusion	2–4 days	500
20	Film coating	2–3 days	500
21	Planning of development of dosage form (literature review, design of experiments)	1 month	5000
22	Preparation of batch (1 batch, equipment + 2 specialists involved)	4 days	3000
23	Preparation of 25 batches (equipment + 2 specialists involved)	6 months	80000
24	Summary, preparation of the report	1 month	5000
25	TOTAL: planning + preparation of 25 batches + summary and report	7 months	90000
26	TECHNOLOGIES with complex analytics	12 months	30000

Pharmaceutical analyses and technologies

Laboratory of Finished Dosage Forms