Research projects

Projects conducted by the Computational Systems Biology Team, led by Dr.sc.ing. Egils Stalidzāns, are listed on the Computational Systems Biology Group website.

• Participation of Rīga Stradiņš University in the Horizon Europe Programme (coordinator: Sandra Vasiļevska), 01.06.2025–30.11.2029, No.1.1.1.5/3/25/I/014, funded by the European Regional Development Fund (ERDF) and the national budget and including the implementation of the ESFRI/ERIC National Partnership Plan and Action Plan for the European Life Science Infrastructure Consortium for Biological Information (ELIXIR).
• Systemic and muscle tissue-specific metabolic adaptations to EXercise and POlyphenol supplementation in aging: modulatory effects of SEstrins (EXPOSE) (co-ordinator: Asst. Prof. Dace Reihmane), 01.04.2024–31.03.2026, No. RSU-ZG-2024/1-0009, Internal consolidation of RSU and external consolidation of RSU with LASE (No. 5,2,1,1.i.0/2/24/I/CFLA/005), financed under the European Union's Recovery and Resilience Facility and the national budget
• Hypothalamic mechanisms of High-Calorie intervention in ALS (HiCALS) (co-ordinator: Apl. Prof. Dr. F. Roselli, Dept. of Neurology, Ulm University, Germany), 01.06.2023–31.05.2026, No. 7-3-2.N-1873, The EU Joint Programme – Neurodegenerative Disease Research (JPND)
• Multidimensional mechanistic investigations of trans spinal direct current stimulation in motor neuron disease (DC4MND) (co-ordinator: Asst. Prof. M. Bączyk, Department of Neurobiology, Poznan University of Physical Education, Poland), 01.06.2023–31.05.2026, No. 7-3-2.N-1876, The EU Joint Programme – Neurodegenerative Disease Research (JPND)
• The role of clonal hematopoiesis of indeterminate potential as a potential driver of cardiovascular diseases and its association with clinical outcome (with Assoc. Prof. K. Trušinskis), 03.01.2022–30.12.2024, No. lzp-2021/1-0293, Latvian Council of Science (LCS)
• Discovering biomarkers of disease progression and variability in Charcot-Marie-Tooth neuropathy (with Asst. Prof. V. Ķēniņa), 03.01.2022–30.12.2024, No. lzp-2021/1-0327, Latvian Council of Science (LCS)
• Diagnostic accuracy of artificial intelligence systems for radiographic caries detection and high-quality dataset of annotated radiographs (Dr S. Uribe), 26.07.2021–25.07.2022, No. 46-23/9/2021, RSU Internal Grant
• Uncovering the aetiology of primary immunodeficiency in children (with Assoc. Prof. N. Kurjāne), 01.07.2021–30.06.2024, No. 2, MikroTik/The RSU Foundation
• PRecisiOn medicine in CAD patients: artificial intelliGence for integRated gEnomic, functional and anatomical aSSessment of the coronary collateral circulation (PROGRESS) (Coordinator: prof. J. Erdmann, Universität zu Lübeck, Germany), 01.05.2021–30.04.2024, No. ES RTD/2021/3, ERA-NET PerMed
• Predominantly primary antibody deficiencies among adults: solving aetiology and causes of clinical variability (with Assoc. Prof. N. Kurjāne), 01.01.2021–31.12.2023, No. lzp-2020/1-0269, Latvian Council of Science (LCS)
• Elucidating comprehensive aetiology of cervical insufficiency to foster timely diagnosis of preterm delivery and prevent adverse outcomes in obstetrics (with Prof. D. Rezeberga), 01.01.2021–31.12.2023, No. lzp-2020/1-0042, Latvian Council of Science (LCS)
• Towards Implementing the RSU Data Repository and the FAIR Data Principles, 01.02.2021–31.01.2022, No. 1, MikroTik/The RSU Foundation
• Using Machine Learning to Model the Complex Interplay Between Diet, Genetic Factors and Mitochondria in Coronary Artery Disease (Dr B. Vilne), 01.12.2020–31.12.2021, No. lzp-2020/2-0338, Latvian Council of Science (LCS)
• Investigating the Role of Genome Instability in Male Infertility (with Dr J. Ērenpreiss), 01.12.2020–31.12.2021, No. lzp-2020/1-0111, Latvian Council of Science (LCS)
• Hypoxia-associated biomarkers in HER2+ breast cancer cell lines for personalized therapy (with Asst. Prof. I. Čakstiņu), 01.07.2020–30.06.2021, No. 5-1/252/2020, RSU Internal Grant
• A multi-disciplinary approach to COVID19 and other futures monitoring, control and control of epidemics in Latvia (with Prof. U. Dumpis), 01.07.2020–31.12.2020, No. VPP-COVID-2020/1-0008, National research program for the mitigation of COVID-19
• Establishment of a COVID-19 related sample biobank and associated data integrated platform in Latvia (with Assoc. Prof. J. Kloviņš), 01.07.2020–31.12.2020, No. VPP-COVID-2020/1-0016, National research program for the mitigation of COVID-19