Work experience
2015 - Present | Acting Assistant ProfessorFaculty of Medicine, Department of Human Physiology and Biochemistry |
2013 - Present | Senior researcherInstitute of Cardiology and regenerative medicine, University of Latvia |
2014 - 2015 | Senior lecturerFaculty of Medicine, Department of Human Physiology and Biochemistry |
2007 - 2013 | ResearcherInstitute of Experimental and clinical medicine, University of Latvia |
2007 - 2012 | TeacherFaculty of Biology, Department of Human and Animal Physiology, University of Latvia |
Education and training
2007 - 2013 | Dr.Biol.University of Latvia Title of the doctoral thesis "Vazodilatācijas intensitātes un insulīna rezistences rādītāju saistība ar endoteliālo (dis)funkciju raksturojošo signālmolekulu koncentrācijām hroniskiem smēķētājiem"; Scientific supervisor: Dr.biol, Asoc.prof.Pēteris Tretjakovs |
2004 - 2006 | Master’s degree of Biological SciencesUniversity of Latvia Neuroscience Neurophysiology Sport's physiology Comparative physiology of Human and Animal Sensory physiology Physiology of cardiovascular system Digestive physiology Microbiology |
2001 - 2004 | Bachelor's degree of Biology SciencesThe University of Latvia |
Achievements
Continuing education a.o. qualification upgrade
13.06.-06.08.2016. Online courses of "Advanced Neurobiology I", organized by Peking University; Certificate
01.06.2016. RSU PIC organized lecture/seminar "Kanādas Britu Kolumbijas universitātes pieredze flipped classroom īstenošanā". Lektors Asoc.prof. Andis Klegeris; Apliecinājums Nr. 2016/216, 4 ak./st.
26.05.2016. RSU PIC organised courses of "Europass dokumentu portfolio"; Apliecinājums Nr.2016/314; 3 ak./st.
17.-18.03.2016. Riga Stradiņš University 15.Scientific conference; Certificate
03.10.2014. Thermo Fisher Scientific "Days of Science 2014" held in Riga; Certificate
10.-11.05.2013. Internationale Concerence "1st Meeting of the Baltic Physiological Societies" held in Kaunas, Lithuania; Certificate No. PS-10-148-16049; 12 c/p
29.-30.03.2012. Riga Stradiņš University 11.Scientific Conference; Certificate.
26.-29.07.2011. European Atherosclerosis Society organized congress "79th Annual Congress of the European Atherosclerosis Society" Gothenburg, Sweden; Certificate
01.03.-21.05.2011. ERASMUS study practice in Maastricht (The Netherlands), The Laboratory for Metabolism and Vascular Medicine, Cardiovascular Research Institute Maastricht (CARIM).
14.-15.04.2011. Riga Stradiņš University 10.Scientific Conference; Certificate.
23.-24.09.2010. Centro Nacionale Investigaciones Cardiovasculares organized Conference/Workshop "New insights into cell & tissue interactions in cardiovascular development and disease" Madrid, Spain; Certificate
Field of research
- Cardiovascular disease risk factors and their detection and possible prevention;
- Metabolic syndrome, prediabetes, diabetes;
- Arterial hypertension;
- inflammatatory biomarkers (cytokines, growth factors) and oxidative stress influence to the microvasculature; significance of oxidative stress to the ageing processes;
- Exogenous factors influence to the ageing processes; its evaluation/ detection and procedure complex to reduce this process.
Lectured study course
Adaptation of Bodily Functions
Normal Physiology
Normal Physiology and Neurophysiology
Physiology
Supervised and reviewed student research papers
Supervised:
course work: 1
bachelor's theses: 1
Consultant :
bachelor's theses: 1
Projects
Senior researcher, project manager; «Pranamat ECO akupresūras paklājiņa lokāla ietekme uz mikrocirkulācijas intensitātes, vielmaiņas un seruma neiropeptīdu koncentrācijas izmaiņām pacientiem ar mugurkaulāja spondilozi». Līgumpētījuma Nr. LIG/INT/2013-24, LU reģ.Nr. 2885 (2013 – 2014).
Researcher; «Diabēta un sirds-asinsvadu slimību farmakoģenētika, zāļu
mērķreceptoru testēšana». Projekts Nr.2010. 10-4/VPP-4, LU projekts Y3-26513-003 (2010 – 2012).
Researcher; «Saistība starp neopterīnu un iekaisuma biomarķieriem aterosklerozes pacientiem». Eiropas Ekonomikas zonas finanšu instrumenta grantu shēmas „Akadēmiskie pētījumi" apakšprojekts (sadarbībā ar Insbrukas Medicīnas Universitāti) Nr.EEZ08AP-5/2 (2009 – 2010).
Researcher; «Aptaukošanās izraisīto slimību un cukura diabēta mūsdienīgu agrīnās diagnostikas, profilakses un terapijas pasākumu izstrāde». Valsts pētījumu programmas Medicīnā Nr.8 LZP projekts 07-VP-ZP; LU projekts Y3-23464-003 (2007 – 2009).
Researcher; «Jaunas pieejas eksogēno veselības riska faktoru izraisīto traucējumu diagnostikā». IZM-LU proj. Nr. Y2-ZP80-003 (2007 – 2008).
Awards and recognitions
2004. Certificate of Recognition of the Rector of University of Latvia.
Publications
Research articles
Pranamat ECO akupresūras-masāžas paklājiņš. Efektivitātes novērtējums muguras sāpju novēršanai / I.Miķelsone, G.Krieviņa, Dz.Vāvere // DOCTUS – žurnāls ārstiem un farmaceitiem, jūnijs 2015, 6 [171], 48–51.
The acute effects of cigarette smoking on microvascular responsiveness and haemodynamic measurements in healthy male smokers / I.Mikelsone, P.Tretjakovs, A.Jurka ...[et al.] // Collection of Scientific Papers 2011 : Research articles in medicine & pharmacy / Rīga Stradiņš University. - Riga, 2012. - P.134-141.
The effect of chronic cigarette smoking on microvascular function, insulin resistance and inflammatory state / Mikelsone I., Bormane I., Simsone Z., Jurka A., Tretjakovs P // Environmental and Experimental Biology, 2011, 9: 23–28.
Circulating adhesion molecules, matrix metalloproteinase-9, plasminogen activator inhibitor-1, and myeloperoxidase in coronary artery disease patients with stable and unstable angina / Tretjakovs P.,Jurka A., Mikelsone I., Elksne K., Krieviņa G., Reihmane D., Verbovenko J., Bahs G // Clinica Chimica Acta, 2011.10, doi: 10.10164.
Relation of inflammatory chemokines to insulin resistance and hypoadipo-nectinemia in coronary artery disease patients / Tretjakovs P., Jurka A., Bormane I., Mackevics V., Mikelsone I., Balode L.,Reihmane D., Stukena I., Bahs G., Aivars J.I., Pirags V // European Journal of Internal Medicine, 2009, 20(7): 712–717.
Relation of Endothelial dysfunction and adipokines levels to insulin resistance in metabolic syndrome patients / Tretjakovs P., Jurka A., Bormane I., Miķelsone I., Reihmane D., Balode L., Jaunalksne I., Mackēvičs V., Stuķēna I., Bahs G., Lejnieks A., Aivars J.I., Pīrāgs V // Proceeding of the Latvian Academy of Sciences, 2009, 63(4-5): 222–227.
Alterations of tumor necrosis factor-alpha, endothelin-1 and vasomotor activity in patients with insulin resistance / Tretjakovs P., Jurka A., Bormane I., Miķelsone I., Reihmane D., Balode L., Aivars J.I., Stukēna I., Bahs G., Lejnieks A // RSU Zinātniskie raksti, Research articles in medicine&pharmacy, 2009.
Changes of plasminogen activator inhibitor-1, adhesion molecules, and endothelium-dependent vasodilatation and their relationship to insulin resistance in metabolic syndrome patients / Tretjakovs P., Jurka A., Bormane I., Miķelsone I., Reihmane D., Balode L., Aivars J.I., Stukēna I., Bahs G // RSU Zinātniskie raksti, Research articles in medicine&pharmacy, 2009.
Alteration of serum adhesion molecules and cutaneous endothelium-dependent vasodilatation in insulin resistant obese patients / Bormane I., Tretjakovs P., Jurka A., Mikelsone I., Reihmane D., Balode L., Elksne K., Aivars J.I., Stukena I., Cirule K., Bahs G., Pirags V // Acta Universitatis Latviensis, Biology, 2009, 753: 107–115.
Adipokines levels and markers of endothelial dysfunction in metabolic syndrome patients with insulin resistance / Tretjakovs P., Jurka A., Bormane I., Mikelsone I., Reihmane D., Balode L., Elksne K., Jaunalksne I., Mackevics V., Stukena I., Bahs G., Lejnieks A., Aivars J.I., Pirags V // Experimental and Clinical Endocrinology&Diabetes, 2009 (Nr ECED-08-2009-0242-Diabetes-Art).
Increased TNF-alpha levels and vasomotor dysfunction in hypertensive patients with insulin resistance / Jurka A., Tretjakovs P., Bormane I., Reihmane D., Mikelsone I., Jirgensons J., Bahs G., Martinsons A // Current Advances in Heart Disease, MEDIMOND International Proceedings, 2008: 219–223.
Abstracts
Alterations in cutaneous vasomotor responses and inflammatory state affected by chronic cigarette smoking and aging / I.Mikelsone, I.Bormane, Z.Simsone, P.Tretjakovs // Atherosclerosis Supplements. - Vol.12, N 1 (2011, June), p.182.
International Conferences
Relationship of Myeloperoxidase to Adiponectin and High-Density Lipoprotein (HDL) In Healthy Cigarette Smokers / I. Mikelsone, A. Plinta, A. Jurka, P. Tretjakovs // Poster presentation [Cardio P-1] / 1st Meeting of the Baltic Physiological Societies, Kaunas, Lithuania, May 10-11, 2013.
Alterations in cutaneous vasomotor responses and inflammatory state affected by chronic cigarette smoking and aging / Mikelsone I., Bormane I., Simsone Z., Tretjakovs P // Poster presentation 4.222 / The 79th European Atherosclerosis Society (EAS) Annual Congress, Gothenburg, Sweden, June 26-29, 2011.
The acute effects of cigarette smoking on microvascular reactivity and haemodynamic measurements in healthy young and adult men / Mikelsone I., Bormane I., Simsone Z., Tretjakovs P // Poster presentation P13 [4070] / The Annual Meeting of the Scandinavian Physiological Society, Bergen, Norway, August 12-14, 2011. // Acta Physiologica, 2011, 202 (685): P13 [4070].
Evaluation of sE-selectin, insulin resistance and obesity influence to endothelium dependent vasodilatation in 2TDM patients / Mikelsone I., Bormane I., Jurka A., Tretjakovs P // Poster presentation No.7./ New insights into cell & tissue interactions in cardiovascular development and disease / Madrid, Spain, September 23 - 24, 2010// Centro Nacional de Investigaciones Cardiovasculares, Abstract Booklet, 2010.
Alterations of adipokines and cutaneous vasomotor responses in metabolic syndrome patients with insulin resistance / Mikelsone I., Jurka A., Bormane I, Reihmane D., Balode L., Aivars J.I., Tretjakovs P // Poster presentation P22. / The Annual Meeting of the Scandinavian Physiological Society. Uppsala, Sweden, August 14-16, 2009.// Acta Physiologica, 2009, V 196 (Suppl. 671: 111(P22).
Vasomotor dysfunction and alterations of adipokines in metabolic syndrome patients with insulin resistance / Mikelsone I., Jurka A., Reihmane D., Bormane I., Balode L., Aivars J.I., Tretjakovs P // Poster presentation 505 (P5AM-4-6 ). / The 14th International Congress of Physiological Sciences (IUPS). Kyoto, Japan, July 27 - August 1, 2009. // The Journal of Physiological Sciences, 2009, No. 59 (Suppl. 1): 505: P5AM-4-6.
Conferences and Seminars in Latvia
Miķelsone I. Pranamat ECO akupresūras masāžas paklājiņa efektivitātes novērtējums. Pētījuma rezultātu apkopojums: referāts / LU EKMI ikkadējais Zinātniskais seminārs, Rīga, 2014.
Miķelsone I. AGE's (advanced glycation end-products) akumulācija audos kā oksidatīvā stresa marķieris diabēta komplikāciju gadījumos: referāts / LU EKMI ikkadējais Zinātniskais seminārs, Rīga, 16.06.2011.
Miķelsone I., Jurka A., Bormane I., Tretjakovs P. Adipokīnu, iekaisuma citokīnu un endoteliālās funkcijas pārmaiņu saistība ar insulīna rezistenci metabolā sindroma pacientiem: referāts. / LU 68.konference, Bioloģijas sekcija, 2010.
Miķelsone I. Eksogēno faktoru ietekme uz endotēlija funkcijām: referāts. / LU 67.konference, Bioloģijas sekcija, 2009.
Miķelsone I. Osteorefleksoterapijas ietekme uz asins mikrocirkulāciju un vazomociju: referāts. / LU 66.konference, Bioloģijas sekcija, 2008.
Contacts

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