Skip to main content

Work experience

2015 - Present

Acting Assistant Professor

Faculty of Medicine, Department of Human Physiology and Biochemistry

2013 - Present

Senior researcher

Institute of Cardiology and regenerative medicine, University of Latvia

2014 - 2015

Senior lecturer

Faculty of Medicine, Department of Human Physiology and Biochemistry

2007 - 2013

Researcher

Institute of Experimental and clinical medicine, University of Latvia

2007 - 2012

Teacher

Faculty of Biology, Department of Human and Animal Physiology, University of Latvia

Education and training

2007 - 2013

Dr.Biol.

University of Latvia

Title of the doctoral thesis "Vazodilatācijas intensitātes un insulīna rezistences rādītāju saistība ar endoteliālo (dis)funkciju raksturojošo signālmolekulu koncentrācijām hroniskiem smēķētājiem";

Scientific supervisor: Dr.biol, Asoc.prof.Pēteris Tretjakovs

2004 - 2006

Master’s degree of Biological Sciences

University of Latvia

Neuroscience

Neurophysiology

Sport's physiology

Comparative physiology of Human and Animal

Sensory physiology

Physiology of cardiovascular system

Digestive physiology

Microbiology

2001 - 2004

Bachelor's degree of Biology Sciences

The University of Latvia

Achievements

Continuing education a.o. qualification upgrade

13.06.-06.08.2016. Online courses of "Advanced Neurobiology I", organized by Peking University; Certificate

01.06.2016. RSU PIC organized lecture/seminar "Kanādas Britu Kolumbijas universitātes pieredze flipped classroom īstenošanā". Lektors Asoc.prof. Andis Klegeris; Apliecinājums Nr. 2016/216, 4 ak./st.

26.05.2016. RSU PIC organised courses of "Europass dokumentu portfolio"; Apliecinājums Nr.2016/314; 3 ak./st.

17.-18.03.2016. Riga Stradiņš University 15.Scientific conference; Certificate

03.10.2014. Thermo Fisher Scientific "Days of Science 2014" held in Riga; Certificate

10.-11.05.2013. Internationale Concerence "1st Meeting of the Baltic Physiological Societies" held in Kaunas, ​Lithuania; Certificate No. PS-10-148-16049; 12 c/p

29.-30.03.2012. Riga Stradiņš University 11.Scientific Conference; Certificate​.

26.-29.07.2011. European Atherosclerosis Society organized congress "79th Annual Congress of the European Atherosclerosis Society" Gothenburg, Sweden; Certificate

01.03.-21.05.2011. ERASMUS study practice in Maastricht (The Netherlands), The Laboratory for Metabolism and Vascular Medicine, Cardiovascular Research Institute Maastricht (CARIM).

14.-15.04.2011. Riga Stradiņš University 10.Scientific Conference; Certificate​.

23.-24.09.2010. Centro Nacionale Investigaciones Cardiovasculares organized Conference/Workshop "New insights into cell & tissue interactions in cardiovascular development and disease" Madrid, Spain; Certificate

Field of research

  • Cardiovascular disease risk factors and their detection and possible prevention;
  • Metabolic syndrome, prediabetes, diabetes;
  • Arterial hypertension;
  • inflammatatory biomarkers (cytokines, growth factors) and oxidative stress influence to the microvasculature; significance of oxidative stress to the ageing processes;
  • Exogenous factors influence to the ageing processes; its evaluation/ detection and procedure complex to reduce this process.

Lectured study course

Adaptation of Bodily Functions

Normal Physiology

Normal Physiology and Neurophysiology

Physiology

Supervised and reviewed student research papers


Supervised:

course work: 1

bachelor's theses: 1

Consultant :

bachelor's theses: 1

Projects

Senior researcher, project manager; «Pranamat ECO akupresūras paklājiņa lokāla ietekme uz mikrocirkulācijas intensitātes, vielmaiņas un seruma neiropeptīdu koncentrācijas izmaiņām pacientiem ar mugurkaulāja spondilozi». Līgumpētījuma Nr. LIG/INT/2013-24, LU reģ.Nr. 2885 (2013 – 2014).

Researcher; «Diabēta un sirds-asinsvadu slimību farmakoģenētika, zāļu

mērķreceptoru testēšana». Projekts Nr.2010. 10-4/VPP-4, LU projekts Y3-26513-003 (2010 – 2012).

Researcher; «Saistība starp neopterīnu un iekaisuma biomarķieriem aterosklerozes pacientiem». Eiropas Ekonomikas zonas finanšu instrumenta grantu shēmas „Akadēmiskie pētījumi" apakšprojekts (sadarbībā ar Insbrukas Medicīnas Universitāti) Nr.EEZ08AP-5/2 (2009 – 2010).

Researcher; «Aptaukošanās izraisīto slimību un cukura diabēta mūsdienīgu agrīnās diagnostikas, profilakses un terapijas pasākumu izstrāde». Valsts pētījumu programmas Medicīnā Nr.8 LZP projekts 07-VP-ZP; LU projekts Y3-23464-003 (2007 – 2009).

Researcher; «Jaunas pieejas eksogēno veselības riska faktoru izraisīto traucējumu diagnostikā». IZM-LU proj. Nr. Y2-ZP80-003 (2007 – 2008).

Awards and recognitions

2004. Certificate of Recognition of the Rector of University of Latvia.

Publications

Research articles​​

Pranamat ECO akupresūras-masāžas paklājiņš. Efektivitātes novērtējums muguras sāpju novēršanai​ / I.Miķelsone, G.Krieviņa, Dz.Vāvere // DOCTUS – žurnāls ārstiem un farmaceitiem, jūnijs 2015, 6 [171], 48–51.

The acute effects of cigarette smoking on microvascular responsiveness and haemodynamic measurements in healthy male smokers / I.Mikelsone, P.Tretjakovs, A.Jurka ...[et al.] // Collection of Scientific Papers 2011 : Research articles in medicine & pharmacy / Rīga Stradiņš University. - Riga, 2012. - P.134-141.

The effect of chronic cigarette smoking on microvascular function, insulin resistance and inflammatory state / Mikelsone I., Bormane I., Simsone Z., Jurka A., Tretjakovs P // Environmental and Experimental Biology, 2011, 9: 23–28.

Circulating adhesion molecules, matrix metalloproteinase-9, plasminogen activator inhibitor-1, and myeloperoxidase in coronary artery disease patients with stable and unstable angina / Tretjakovs P.,Jurka A., Mikelsone I., Elksne K., Krieviņa G., Reihmane D., Verbovenko J., Bahs G // Clinica Chimica Acta, 2011.10, doi: 10.10164.

Relation of inflammatory chemokines to insulin resistance and hypoadipo-nectinemia in coronary artery disease patients / Tretjakovs P., Jurka A., Bormane I., Mackevics V., Mikelsone I., Balode L.,Reihmane D., Stukena I., Bahs G., Aivars J.I., Pirags V // European Journal of Internal Medicine, 2009, 20(7): 712–717.

Relation of Endothelial dysfunction and adipokines levels to insulin resistance in metabolic syndrome patients / Tretjakovs P., Jurka A., Bormane I., Miķelsone I., Reihmane D., Balode L., Jaunalksne I., Mackēvičs V., Stuķēna I., Bahs G., Lejnieks A., Aivars J.I., Pīrāgs V // Proceeding of the Latvian Academy of Sciences, 2009, 63(4-5): 222–227.

Alterations of tumor necrosis factor-alpha, endothelin-1 and vasomotor activity in patients with insulin resistance / Tretjakovs P., Jurka A., Bormane I., Miķelsone I., Reihmane D., Balode L., Aivars J.I., Stukēna I., Bahs G., Lejnieks A // RSU Zinātniskie raksti, Research articles in medicine&pharmacy, 2009.

Changes of plasminogen activator inhibitor-1, adhesion molecules, and endothelium-dependent vasodilatation and their relationship to insulin resistance in metabolic syndrome patients / Tretjakovs P., Jurka A., Bormane I., Miķelsone I., Reihmane D., Balode L., Aivars J.I., Stukēna I., Bahs G // RSU Zinātniskie raksti, Research articles in medicine&pharmacy, 2009.

Alteration of serum adhesion molecules and cutaneous endothelium-dependent vasodilatation in insulin resistant obese patients / Bormane I., Tretjakovs P., Jurka A., Mikelsone I., Reihmane D., Balode L., Elksne K., Aivars J.I., Stukena I., Cirule K., Bahs G., Pirags V // Acta Universitatis Latviensis, Biology, 2009, 753: 107–115.

Adipokines levels and markers of endothelial dysfunction in metabolic syndrome patients with insulin resistance / Tretjakovs P., Jurka A., Bormane I., Mikelsone I., Reihmane D., Balode L., Elksne K., Jaunalksne I., Mackevics V., Stukena I., Bahs G., Lejnieks A., Aivars J.I., Pirags V // Experimental and Clinical Endocrinology&Diabetes, 2009 (Nr ECED-08-2009-0242-Diabetes-Art).

Increased TNF-alpha levels and vasomotor dysfunction in hypertensive patients with insulin resistance / Jurka A., Tretjakovs P., Bormane I., Reihmane D., Mikelsone I., Jirgensons J., Bahs G., Martinsons A // Current Advances in Heart Disease, MEDIMOND International Proceedings, 2008: 219–223.


Abstracts​​

Alterations in cutaneous vasomotor responses and inflammatory state affected by chronic cigarette smoking and aging / I.Mikelsone, I.Bormane, Z.Simsone, P.Tretjakovs // Atherosclerosis Supplements. - Vol.12, N 1 (2011, June), p.182.

International Conferences

Relationship of Myeloperoxidase to Adiponectin and High-Density Lipoprotein (HDL) In Healthy Cigarette Smokers / I. Mikelsone, A. Plinta, A. Jurka, P. Tretjakovs // Poster presentation [Cardio P-1] / 1st Meeting of the Baltic Physiological Societies, Kaunas, Lithuania, May 10-11, 2013.

Alterations in cutaneous vasomotor responses and inflammatory state affected by chronic cigarette smoking and aging / Mikelsone I., Bormane I., Simsone Z., Tretjakovs P // Poster presentation 4.222 / The 79th European Atherosclerosis Society (EAS) Annual Congress, Gothenburg, Sweden, June 26-29, 2011.

The acute effects of cigarette smoking on microvascular reactivity and haemodynamic measurements in healthy young and adult men / Mikelsone I., Bormane I., Simsone Z., Tretjakovs P // Poster presentation P13 [4070] / The Annual Meeting of the Scandinavian Physiological Society, Bergen, Norway, August 12-14, 2011. // Acta Physiologica, 2011, 202 (685): P13 [4070].​

Evaluation of sE-selectin, insulin resistance and obesity influence to endothelium dependent vasodilatation in 2TDM patients / Mikelsone I., Bormane I., Jurka A., Tretjakovs P // Poster presentation No.7./ New insights into cell & tissue interactions in cardiovascular development and disease / Madrid, Spain, September 23 - 24, 2010// Centro Nacional de Investigaciones Cardiovasculares, Abstract Booklet, 2010.

Alterations of adipokines and cutaneous vasomotor responses in metabolic syndrome patients with insulin resistance / Mikelsone I., Jurka A., Bormane I, Reihmane D., Balode L., Aivars J.I., Tretjakovs P // Poster presentation P22. / The Annual Meeting of the Scandinavian Physiological Society. Uppsala, Sweden, August 14-16, 2009.// Acta Physiologica, 2009, V 196 (Suppl. 671: 111(P22).

Vasomotor dysfunction and alterations of adipokines in metabolic syndrome patients with insulin resistance / Mikelsone I., Jurka A., Reihmane D., Bormane I., Balode L., Aivars J.I., Tretjakovs P // Poster presentation 505 (P5AM-4-6 ). / The 14th International Congress of Physiological Sciences (IUPS). Kyoto, Japan, July 27 - August 1, 2009. // The Journal of Physiological Sciences, 2009, No. 59 (Suppl. 1): 505: P5AM-4-6.

Conferences and Seminars in Latvia

Miķelsone I. Pranamat ECO akupresūras masāžas paklājiņa efektivitātes novērtējums. Pētījuma rezultātu apkopojums: referāts / LU EKMI ikkadējais Zinātniskais seminārs, Rīga, 2014.

Miķelsone I. AGE's (advanced glycation end-products) akumulācija audos kā oksidatīvā stresa marķieris diabēta komplikāciju gadījumos: referāts / LU EKMI ikkadējais Zinātniskais seminārs, Rīga, 16.06.2011.

Miķelsone I., Jurka A., Bormane I., Tretjakovs P. Adipokīnu, iekaisuma citokīnu un endoteliālās funkcijas pārmaiņu saistība ar insulīna rezistenci metabolā sindroma pacientiem: referāts. / LU 68.konference, Bioloģijas sekcija, 2010.

Miķelsone I. Eksogēno faktoru ietekme uz endotēlija funkcijām: referāts. / LU 67.konference, Bioloģijas sekcija, 2009.

Miķelsone I. Osteorefleksoterapijas ietekme uz asins mikrocirkulāciju un vazomociju: referāts. / LU 66.konference, Bioloģijas sekcija, 2008.

Contacts

Colleagues

Jānis Gardovskis
Head of the Unit, Academic Staff, Chair of the Senate
Ilze Grope
Dean, Academic Staff
Sandra Lejniece
Dean, Head of Study Programme
Gunta Lazdāne
Academic Staff, Director
Edvīns Miklaševičs
Academic Staff, Director
Gunta Ancāne
Head of the Department, Academic Staff
Maija Eglīte
Head of the Department, Academic Staff
Dace Gardovska
Head of the Department, Academic Staff, Director of Strategic Relations
Ilona Hartmane
Academic Staff
Regīna Kleina
Academic Staff
Juta Kroiča
Head of the Department, Academic Staff, Deputy Chair of the Senate
Gaida Krūmiņa
Academic Staff
Guna Laganovska
Head of the Department, Academic Staff
Ināra Logina
Academic Staff
Gunta Purkalne
Academic Staff, Leading Researcher
Ilze Štrumfa
Head of the Department, Academic Staff