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Pharmaceutical Biochemistry and Interpretation of Biochemical Tests
Study Course Description
Course Description Statuss:Approved
Course Description Version:5.00
Study Course Accepted:07.11.2022 10:02:08
| Study Course Information | |||||||||
| Course Code: | CFUBK_027 | LQF level: | Level 7 | ||||||
| Credit Points: | 2.00 | ECTS: | 3.00 | ||||||
| Branch of Science: | Basic Sciences of Medicine, including Pharmacy | Target Audience: | Pharmacy | ||||||
| Study Course Supervisor | |||||||||
| Course Supervisor: | Ināra Nokalna | ||||||||
| Study Course Implementer | |||||||||
| Structural Unit: | Department of Human Physiology and Biochemistry | ||||||||
| The Head of Structural Unit: | |||||||||
| Contacts: | Riga, 16 Dzirciema Street, cfbk rsu[pnkts]lv, +371 67061550 | ||||||||
| Study Course Planning | |||||||||
| Full-Time - Semester No.1 | |||||||||
| Lectures (count) | 5 | Lecture Length (academic hours) | 3 | Total Contact Hours of Lectures | 15 | ||||
| Classes (count) | 3 | Class Length (academic hours) | 3 | Total Contact Hours of Classes | 9 | ||||
| Total Contact Hours | 24 | ||||||||
| Study course description | |||||||||
| Preliminary Knowledge: | Medical biochemistry and normal physiology of FF 2nd and 3rd course level. | ||||||||
| Objective: | Promote the acquisition of knowledge about the detoxification processes taking place in human body; importance of biochemical indicators used in diagnostics. | ||||||||
| Topic Layout (Full-Time) | |||||||||
| No. | Topic | Type of Implementation | Number | Venue | |||||
| 1 | Enzymes, principle of operation, influencing factors, operational regulation options. Medication principle of operation. | Lectures | 1.00 | auditorium | |||||
| 2 | Function of cytochrome P 450. | Lectures | 1.00 | auditorium | |||||
| 3 | Conjugating substances, their formation, role. Enzymes. | Lectures | 1.00 | auditorium | |||||
| 4 | Amino acids as conjugating substances. | Lectures | 1.00 | auditorium | |||||
| 5 | Interpretation of biochemical analysis - blood counts. | Lectures | 1.00 | auditorium | |||||
| 6 | Interpretation of biochemical analysis - biochemical values. | Classes | 1.00 | laboratory | |||||
| 7 | Blood count Nitrogen metabolism indicators. Enzymes in diagnostics. | Classes | 1.00 | laboratory | |||||
| 8 | Presentation of research paper. | Classes | 1.00 | laboratory | |||||
| Assessment | |||||||||
| Unaided Work: | Independent learning of theoretical topics through sources, such as scientific books, publications. | ||||||||
| Assessment Criteria: | • Participation in practical classes, problem solving (50%). • At the final examination, the examination is a presentation of a scientific work on the given study course (50%). | ||||||||
| Final Examination (Full-Time): | Exam (Written) | ||||||||
| Final Examination (Part-Time): | |||||||||
| Learning Outcomes | |||||||||
| Knowledge: | After successful completion of the course the student will be able to: • tell about the role of cytochrome P450 in metabolism, principle of operation; • define conjugated molecule formation and the role of in metabolism; • describe the main detoxification processes in the body; • interpret diagnostic biochemical parameters. | ||||||||
| Skills: | Will be able to explain: • Xenobiotics development chances in the body; • Cytochrome P 450 operating principles; • Conjugated molecule formation processes and the role of in detoxification. Will be able to evaluate detoxification process and differences in various organs. Will be able to evaluate the diagnostic significance of biochemical indicators. | ||||||||
| Competencies: | The student will not be able to apply the acquired knowledge about ongoing body detoxification processes; their integration and regulation. Will be able to understand the biochemical diagnostic indicators. | ||||||||
| Bibliography | |||||||||
| No. | Reference | ||||||||
| Required Reading | |||||||||
| 1 | Sandra Lejniece. Klīniskā hematoloģija. Medicīnas apgāds, 2020 | ||||||||
| 2 | V.W.. Rodwell, D.A. Bender, P.J. Kennelly, P.A. Weil. Harper's Illustrated Biochemistry. 31st ed., 2018.by Appleton & Lange, Stamford, CT. 807. | ||||||||
| 3 | A. Balode. Laboratoriskā diagnostika. Nacionālais apgāds, 2008 (akceptējams izdevums) | ||||||||
| Additional Reading | |||||||||
| 1 | R.A. Harvey, D.R. Ferrier. Lippincott's Illustrated Reviews: Biochemistry (Lippincott's Illustrated Reviews Series), 2021: 544. | ||||||||
| 2 | Klīnisko analīžu rokasgrāmata E. Gulbja laboratorija, 2018 | ||||||||
| Other Information Sources | |||||||||
| 1 | Pub Med un citas datu bāzes. | ||||||||
