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Embryology
Study Course Description
Course Description Statuss:Approved
Course Description Version:6.00
Study Course Accepted:22.02.2024 13:15:35
| Study Course Information | |||||||||
| Course Code: | MK_057 | LQF level: | Level 7 | ||||||
| Credit Points: | 1.00 | ECTS: | 1.50 | ||||||
| Branch of Science: | Clinical Medicine; Histology and Cytology | Target Audience: | Dentistry | ||||||
| Study Course Supervisor | |||||||||
| Course Supervisor: | Māra Pilmane | ||||||||
| Study Course Implementer | |||||||||
| Structural Unit: | Department of Morphology | ||||||||
| The Head of Structural Unit: | |||||||||
| Contacts: | Riga, 9 Kronvalda boulevard, aaiak rsu[pnkts]lv, +371 67061551 | ||||||||
| Study Course Planning | |||||||||
| Full-Time - Semester No.1 | |||||||||
| Lectures (count) | 6 | Lecture Length (academic hours) | 2 | Total Contact Hours of Lectures | 12 | ||||
| Classes (count) | 2 | Class Length (academic hours) | 2 | Total Contact Hours of Classes | 4 | ||||
| Total Contact Hours | 16 | ||||||||
| Study course description | |||||||||
| Preliminary Knowledge: | Biology, histology, anatomy and genetics. | ||||||||
| Objective: | Students develop understanding of the development of embryology; basic human development (fertilization, implantation, bi- and trilaminar embryo, placentation, development of three germ layers); of the main cellular, subcellular and molecular processes (induction, determination, differentiation and growth), and of processes at all stages of embryogenesis and fetogenesis. Students develop understanding of histogenesis and organogenesis of particular tissues and organs. Students acquire knowledge of critical periods, critical factors and different congenital and developmental anomalies that arise at different periods of intrauterine life. Students acquire knowledge of achievements in modern experimental embryology and their practical use in daily work of a doctor, and of the elements and significance of comparative embryology. | ||||||||
| Topic Layout (Full-Time) | |||||||||
| No. | Topic | Type of Implementation | Number | Venue | |||||
| 1 | Teratology. Main terms. Historical aspects of embryology content and tasks. Experimental embryology. Periods of intrauterine life. Different gametogenesis. Reproductive cells. Fertilisation. Cleavage. Implantation. | Lectures | 1.00 | Institute of Anatomy and Anthropology | |||||
| 2 | Development of bilateral embryo. Development of extraembryonic structures. Gastrulation and neurulation. Development of trilaminar embryo. Embryonal folding. Placenta. Foetal membranes. Umbilical cord. | Lectures | 1.00 | Institute of Anatomy and Anthropology | |||||
| 3 | Main principles in development of axial skeleton, skull, limbs, and muscles. Main principles and stages in development of the heart and main blood vessels; urogenital system; skin and endocrine system. | Lectures | 1.00 | Institute of Anatomy and Anthropology | |||||
| 4 | Development of head and neck. Development of oral cavity and tongue. Main principles and stages in development of digestive and respiratory systems. | Lectures | 1.00 | Institute of Anatomy and Anthropology | |||||
| 5 | Main development principles into the ontogenetic PNS and PNS; significance of the neural crest cells in the development of the structures. Main principles in the development of sense organs. | Lectures | 1.00 | Institute of Anatomy and Anthropology | |||||
| 6 | Stem cells. | Lectures | 1.00 | Institute of Anatomy and Anthropology | |||||
| 7 | Periods in embryogenesis. Germ cells. Spermatogenesis. Oogenesis. The 1st week of embryogenesis. The 2nd and 3rd week of embryogenesis. Placentation. Development of skeleton, limbs and muscles. Development of heart, lymphatic system, urogenital system. Development of skin and endocrine system. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 8 | Development of face, oral cavity and tongue, digestive, respiratory and nerve system. Development of sense organs. Whole body development. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| Assessment | |||||||||
| Unaided Work: | The students study the given readings and literature independently in accordance with the topics of the course; they analyse the structure of histological and embryological slides in the laboratory and prepare the protocols of their practical work. | ||||||||
| Assessment Criteria: | • Laboratory class protocols of appropriate quality finished and submitted in due time; • Multiple choice examination in combination with practical analysis of specimens at the end of the course. 6 lectures; 2 classes; Semester pass after handing in appropriately prepared protocols and attended practical classes and lectures; final written exam with multiple choice questions and 5 slide recognition (50/50). During the examination, the students’ theoretical knowledge of embryonic tissue and organ morphology and practical skills in analyzing specimens are tested. Students show how to specify age-related changes in tissues and organs. They demonstrate their understanding of the development of tissues and organs as well as the ability to relate morphology with processes. | ||||||||
| Final Examination (Full-Time): | Exam (Written) | ||||||||
| Final Examination (Part-Time): | |||||||||
| Learning Outcomes | |||||||||
| Knowledge: | On successful completion of the study course students will be able to demonstrate understanding of embryology and significance of prenatal diagnostic methods, to describe structural features of primordia in tissue and organs at different developmental stages, to define risk periods in histo- and organogenesis, and to analyse the most often observed developmental anomalies. | ||||||||
| Skills: | The student will be able to determine the abnormalities of the human system and organs under a microscope, but will recognize the developmental stages of the face, jaw and neck, as well as the sensory organs, analyze their correspondence to the time of development and standard embryonic structures. Will be able to assess possible teratogenic effects. Will be able to describe embryological schemes. Will be able to interpret and analyze course databases and cited literature sources. | ||||||||
| Competencies: | Students will be able to recognize embryonic tissue and organ morphology and structure in clinical specimens. They can analyse variations at different stages of embryonic development and distinguish between healthy and pathological tissues in specimens. The students will be able to estimate the significance of various inducers on the developmental processes with respect to postnatal life. | ||||||||
| Bibliography | |||||||||
| No. | Reference | ||||||||
| Required Reading | |||||||||
| 1 | Pilmane M., Pļaviņa L., Kavak V. 2016. Embryology and Anatomy for Health Sciences. Rīgas Stradiņa universitāte. 511 lpp. ISBN-10: 9984793915, ISBN-13: 978-9984793917 | ||||||||
| 2 | Pilmane M., Šūmahers G.-H. 2006. Medicīniskā embrioloģija. Rīgas Stradiņa universitāte. 335 lpp. ISBN10: 9984788024, ISBN13: 9789984788029. Latviešu valodā jaunāks, precīzāks, atkārtots izdevums nav pieejams. Esošais izdevums ir akceptējams tā precizitātes dēļ un to ir sarakstījuši katedras docētāji. | ||||||||
| 3 | Sadler T.W. 2018. Langman's Medical Embryology. 14th Edition. LWW. 456 p. ISBN-10:1496383907, ISBN-13:978-1496383907 | ||||||||
| 4 | Schoenwolf Gary C., Bleyl Steven B., Brauer Philip R., Francis-West Philippa H. 2021. Larsen's Human Embryology. 6th Edition. Churchill Livingstone. 560 p. ISBN-10:032369604X, ISBN-13:978-0323696043 | ||||||||
| 5 | Moore Keith L., Persaud T. V. N., Torchia Mark G. 2015. The Developing Human: Clinically Oriented Embryology. 10th Edition. Saunders. 560 p. ISBN-10: 0323313388, ISBN-13: 978-0323313384 | ||||||||
| 6 | Moore Keith L., Persaud T. V. N., Torchia Mark G. 2019. Before We Are Born: Essentials of Embryology and Birth Defects. 10th Edition. Saunders. 350 p. ISBN-10:0323608493, ISBN-13:978-0323608497 | ||||||||
| 7 | Carlson Bruce M. 2019. Human Embryology and Developmental Biology. 6th Edition. Saunders. 496 p. ISBN-10:0323523757, ISBN-13:978-0323523752 | ||||||||
| 8 | Dudek Dr. Ronald W. 2013. High-Yield Embryology. 5th Edition. LWW. 176 p. ISBN-10: 1451176104, ISBN-13: 978-1451176100 | ||||||||
| 9 | Slack Jonathan M. W. 2018. The Science of Stem Cells. 1st Edition. Wiley-Blackwell. 264 p. ISBN-10: 1119235154, ISBN-13: 978-1119235156 | ||||||||
| 10 | Ārvalstu studentiem/For international students | ||||||||
| 11 | Slack Jonathan M. W. 2018. The Science of Stem Cells. 1st Edition. Wiley-Blackwell. 264 p. ISBN-10: 1119235154, ISBN-13: 978-1119235156 | ||||||||
| 12 | Dudek Dr. Ronald W. 2013. High-Yield Embryology. 5th Edition. LWW. 176 p. ISBN-10: 1451176104, ISBN-13: 978-1451176100 | ||||||||
| 13 | Carlson Bruce M. 2019. Human Embryology and Developmental Biology. 6th Edition. Saunders. 496 p. ISBN-10:0323523757, ISBN-13:978-0323523752 | ||||||||
| 14 | Moore Keith L., Persaud T. V. N., Torchia Mark G. 2019. Before We Are Born: Essentials of Embryology and Birth Defects. 10th Edition. Saunders. 350 p. ISBN-10:0323608493, ISBN-13:978-0323608497 | ||||||||
| Additional Reading | |||||||||
| 1 | Fehrenbach M., Popowics T. 2016. Illustrated Dental Embryology, Histology, and Anatomy. 4th Edition. Elsevier. 352 p. ISBN: 9780323675536 | ||||||||
| 2 | Blechschmidt E. 2004. The Ontogenetic Basis of Human Anatomy: A Biodynamic Approach to Development from Conception to Birth. 1st Edition. North Atlantic Books. 272 p. ISBN-10: 155643507X, ISBN-13: 978-1556435072. Precīzs embrioloģisko struktūru attainojums, nav atkārtota izdevuma. | ||||||||
| 3 | Blechschmidt E., Gasser R.F. 2012. Biokinetics and Biodynamics of Human Differentiation: Principles and Applications. Reprint Edition. North Atlantic Books. 312 p. ISBN-10: 1583944524, ISBN-13: 978-1583944523 | ||||||||
| 4 | Breedlove Marc S. 2017. Foundations of Neural Development. 1st Edition. Sinauer Associates is an imprint of Oxford University Press. 370 p. ISBN-10: 1605355798 | ||||||||
| 5 | Cochard Larry R. 2012. Netter's Atlas of Human Embryology: Updated Edition. 1st Edition. Saunders. 288 p. ISBN-10: 1455739774, ISBN-13: 978-1455739776 | ||||||||
| 6 | Dudek Dr. Ronald W. 2008. BRS Embryology. 6th Edition. LWW. 336 p. ISBN-10: 1451190387, ISBN-13: 978-1451190380 | ||||||||
| 7 | England Marjorie A. 1983. Colour Atlas of Life Before Birth: Normal Fetal Development. Year Book Medical Pub. 224 p. ISBN-10: 0815131194, ISBN-13: 978-0815131199. Viena no retajām grāmatām, kur publicēti embriju 2D attēli un to histoloģiskās struktūras. Precīzs un korekts embrioloģisko struktūru attainojums un grāmatai nav atkārtota izdevuma. | ||||||||
| 8 | Hombría Castelli-Gair J., Bovolenta P. 2016. Organogenetic Gene Networks: Genetic Control of Organ Formation. 1st Edition. Springer. 376 p. ISBN-10: 3319427652, ISBN-13: 978-3319427652 | ||||||||
| 9 | Lambert Wayne H., Wineski Lawrence E. 2010. Lippincott's Illustrated Q&A Review of Anatomy and Embryology. 1st Edition. LWW. 234 p. ISBN-10: 1605473154, ISBN-13: 978-1605473154. Precīzs embrioloģisko struktūru attainojums; nav atkārtota izdevuma. | ||||||||
| 10 | Schoenwolf Gary C. 2007. Atlas of Descriptive Embryology. 7th Edition. Pearson. 300 p. ISBN-10: 0131585606, ISBN-13: 978-0131585607. Precīzs embrioloģisko struktūru attainojums; nav atkārtota izdevuma. | ||||||||
| Other Information Sources | |||||||||
| 1 | http://www.embryology.ch/indexen.html | ||||||||
| 2 | https://www.ehd.org/movies-index.php | ||||||||
| 3 | https://www.biointeractive.org/classroom-resources/human-em… | ||||||||
| 4 | http://www.lsic.ucla.edu/classes/lifesci/central/ps107/lect… | ||||||||
| 5 | http://www.lsic.ucla.edu/classes/lifesci/central/ps107/lect… | ||||||||
| 6 | https://webcampus.drexelmed.edu/neurobio/embryology/page9/p… | ||||||||
| 7 | https://mediaspace.msu.edu/media/The+Development+of+the+Gas… | ||||||||
| 8 | http://video.brus.club/video/bped-RVWsLk | ||||||||
| 9 | http://www.uco.es/~an1gamoj/MyWeb/cardiovascular_system.html | ||||||||
| 10 | https://www.emouseatlas.org/emap/elearn/Monterde/html/devel… | ||||||||
| 11 | https://transparent-human-embryo.com/ | ||||||||
| 12 | https://embryology.med.unsw.edu.au/embryology/index.php/Mov… | ||||||||
| 13 | https://www.vcbio.science.ru.nl/en/virtuallessons/embryolog… | ||||||||
