.
Clinical Immunology and Immunopharmacology
Study Course Description
Course Description Statuss:Approved
Course Description Version:5.00
Study Course Accepted:09.04.2024 12:02:03
| Study Course Information | |||||||||
| Course Code: | BUMK_011 | LQF level: | Level 7 | ||||||
| Credit Points: | 2.00 | ECTS: | 3.00 | ||||||
| Branch of Science: | Clinical Medicine; Immunology | Target Audience: | Clinical Pharmacy; Medical Services | ||||||
| Study Course Supervisor | |||||||||
| Course Supervisor: | Inese Mihailova | ||||||||
| Study Course Implementer | |||||||||
| Structural Unit: | Department of Biology and Microbiology | ||||||||
| The Head of Structural Unit: | |||||||||
| Contacts: | Riga, 16 Dzirciema Street, bmk rsu[pnkts]lv, +371 67061584 | ||||||||
| Study Course Planning | |||||||||
| Full-Time - Semester No.1 | |||||||||
| Lectures (count) | 5 | Lecture Length (academic hours) | 2 | Total Contact Hours of Lectures | 10 | ||||
| Classes (count) | 4 | Class Length (academic hours) | 3 | Total Contact Hours of Classes | 12 | ||||
| Total Contact Hours | 22 | ||||||||
| Study course description | |||||||||
| Preliminary Knowledge: | Normal anatomy, histology and physiology – must know the structure of the normal immune system, as well as the basic principles of medical genetics, microbiology, biochemistry, pathological physiology and the functions of the immune system. | ||||||||
| Objective: | To promote acquisition of knowledge of the main types of immunopathology and related diseases: immunodeficiencies, autoimmunity, allergies, infections of the immune system, etc.; the most important parameters characterising human immunity, options for the determination thereof, indications, clinical interpretation and use in the diagnosis and differential diagnosis of various diseases; immunoprophylaxis and immunocorrection techniques, agents, indications of use and side effects; clinical immunopharmacology agents. | ||||||||
| Topic Layout (Full-Time) | |||||||||
| No. | Topic | Type of Implementation | Number | Venue | |||||
| 1 | Normal immune defence mechanisms. Specific immunity. Humoral and cellular immunity. Antimicrobial immunity. | Lectures | 1.00 | auditorium | |||||
| 2 | Types of immunopathologies. Clinical manifestations and laboratory diagnosis of immunodeficiency. | Lectures | 1.00 | auditorium | |||||
| 3 | Causes of immunodeficiencies. Primary and secondary immunodeficiencies. Clinical and laboratory diagnostic methods. Immunocompromised patient. Immunoglobulin therapy in case of various immunodeficiencies. | Lectures | 1.00 | auditorium | |||||
| 4 | Allergy as a type of immunopathology. Types of allergies. Immunological diagnosis. Specific hyposensitisation. | Lectures | 1.00 | auditorium | |||||
| 5 | Autoimmunity and autoimmune diseases. Clinical and immunological diagnosis of autoimmune diseases. Autoantibodies. | Lectures | 1.00 | auditorium | |||||
| 6 | Types of immunomodulatory therapies. Immunostimulating and immunosuppressive therapy. Plasmapheresis. | Classes | 1.00 | auditorium | |||||
| 7 | Immunomodulatory therapy for immunodeficiencies. The immunology of vaccination. | Classes | 0.50 | auditorium | |||||
| 8 | Mucosal immunity and stimulation thereof by immunomodulatory agents. | Classes | 0.50 | auditorium | |||||
| 9 | Immunosuppressive therapy. Prednisolone pharmacotherapy, anti-inflammatory and immunosuppressive effects thereof. Cytostatics. Indications for use. Immunological side effects of immunosuppressive therapy. Biological immunomodulatory medicines. | Classes | 1.00 | clinical base | |||||
| 10 | Antiviral immunity-enhancing medicines. Adaptogens, herbal preparations, minerals and vitamins as immunomodulators. Evaluating the effectiveness of immunotherapy: clinical and immunological criteria. Immunotherapy problems. | Classes | 1.00 | clinical base | |||||
| Assessment | |||||||||
| Unaided Work: | To find immunopharmaceuticals from different immunopreparation groups and analyse their mechanisms of immunological action, indications, side effects and methods of administration in a seminar. To prepare an oral presentation on an immunopharmacological preparation. | ||||||||
| Assessment Criteria: | • discussion (Q&A) on theoretical and practical issues in clinical immunopharmacology; • test work; • oral report on an immunopharmacological agent. | ||||||||
| Final Examination (Full-Time): | Exam | ||||||||
| Final Examination (Part-Time): | |||||||||
| Learning Outcomes | |||||||||
| Knowledge: | As a result of completing the study course, students obtain knowledge that allows to: • understand and describe the functioning of the immune system in normal conditions and in case of various immune pathologies; • name and describe the most important immunological test methods that characterise different components of immunity: humoral immunity, cellular immunity, complement system, phagocytosis; • know the aetiology, clinic, immunopathological diagnosis and therapy of immunopathological conditions. | ||||||||
| Skills: | The student will be able to: • orient in the principles of immunotherapy, groups of immunomodulators; • orient in the most important immunomodulatory preparations, their side effects and prevention of the side effects. | ||||||||
| Competencies: | As a result of completing the study course, students will be able to: • monitor the progress of pharmacotherapy in case of immunopathologies, evaluate the results and prepare the necessary information for other medical specialists. | ||||||||
| Bibliography | |||||||||
| No. | Reference | ||||||||
| Required Reading | |||||||||
| 1 | I.Mihailova. J.Kroiča Klīniskā imunoloģija. Grāmatā Klīniskā medicīna 3. daļa A.Lejnieka redakcijā . Rīga 2012. (akceptējams izdevums) | ||||||||
| 2 | Helen Chapel. Essentials of Clinical Immunology. /6th edition/ – Blackwell. 2022 | ||||||||
| 3 | Ch.A.Janeway, Jr., P.Travers. Immunobiology. The Immune System in Health and Disease. 2nd Edition/, Published by Current Biology Ltd. London, San Francisco and Philadelphia, 2022 | ||||||||
| Other Information Sources | |||||||||
| 1 | Mod. Asp. Immunobiology (www.immunotools.com) | ||||||||
| 2 | www.immunelab.boom.ru/immunitet.html | ||||||||
| 3 | www.labinfo.ru/bibl/knigi/nimm/00.htm | ||||||||
| 4 | www.immunologia.narod.ru/1.htm | ||||||||
| 5 | www.med-stud.narod.ru/natur/paediatrics/immdef.html | ||||||||
