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Drug Development
Study Course Description
Course Description Statuss:Approved
Course Description Version:5.00
Study Course Accepted:20.01.2023 11:46:04
| Study Course Information | |||||||||
| Course Code: | FKK_028 | LQF level: | Level 7 | ||||||
| Credit Points: | 2.00 | ECTS: | 3.00 | ||||||
| Branch of Science: | Basic Sciences of Medicine, including Pharmacy; Technology of Drug Forms | Target Audience: | Pharmacy | ||||||
| Study Course Supervisor | |||||||||
| Course Supervisor: | Reinis Vilšķērsts | ||||||||
| Study Course Implementer | |||||||||
| Structural Unit: | Department of Pharmaceutical Chemistry | ||||||||
| The Head of Structural Unit: | |||||||||
| Contacts: | Riga, Dzirciema street 16, A-building. 5th 502.kab., Farmkk rsu[pnkts]lv, +371 67061544 | ||||||||
| Study Course Planning | |||||||||
| Full-Time - Semester No.1 | |||||||||
| Lectures (count) | 8 | Lecture Length (academic hours) | 2 | Total Contact Hours of Lectures | 16 | ||||
| Classes (count) | 8 | Class Length (academic hours) | 2 | Total Contact Hours of Classes | 16 | ||||
| Total Contact Hours | 32 | ||||||||
| Study course description | |||||||||
| Preliminary Knowledge: | Organic and medicinal chemistry, anatomy and physiology. | ||||||||
| Objective: | To give students the opportunity to study further pharmacology and social pharmacy sciences. | ||||||||
| Topic Layout (Full-Time) | |||||||||
| No. | Topic | Type of Implementation | Number | Venue | |||||
| 1 | Economic and legislative aspects of development of new drug substances | Lectures | 1.00 | auditorium | |||||
| 2 | Discovery and development stages of new drug substances | Lectures | 1.00 | auditorium | |||||
| 3 | Pharmaceutical, pharmacokinetic and pharmacodynamic phases of drug activity | Lectures | 1.00 | auditorium | |||||
| 4 | Isosteric modifications | Lectures | 1.00 | auditorium | |||||
| 5 | Main strategies for the development of new drug substances | Lectures | 1.00 | auditorium | |||||
| 6 | Structure activity relationship | Lectures | 1.00 | auditorium | |||||
| 7 | Combinatory synthesis and high-throughput synthesis | Lectures | 2.00 | auditorium | |||||
| 8 | The general approaches for the development of new drug substances. Colloquium | Classes | 2.00 | auditorium | |||||
| 9 | Student presentations about development of certain drug substances searches | Classes | 3.00 | auditorium | |||||
| 10 | Examples of drug design | Classes | 3.00 | auditorium | |||||
| Assessment | |||||||||
| Unaided Work: | Students prepare and present results about design of drug substances. It is recommended to fill in the study course survey, evaluating the existing course content and creating proposals for updating the course. | ||||||||
| Assessment Criteria: | Exam (50% independent work and 50% test). | ||||||||
| Final Examination (Full-Time): | Exam (Written) | ||||||||
| Final Examination (Part-Time): | |||||||||
| Learning Outcomes | |||||||||
| Knowledge: | During course students acquire basic knowledge and expertise about processes used in the development of new drug substances. | ||||||||
| Skills: | After finishing this course students will be able and understand drug creation process, its legal requirements and its economic consequences. | ||||||||
| Competencies: | Methods in creation of new drug substances. | ||||||||
| Bibliography | |||||||||
| No. | Reference | ||||||||
| Required Reading | |||||||||
| 1 | H.P. Rang (ed). Drug Discovery and Development. Elsevier, 2021 | ||||||||
| 2 | A.Hillisch, R.Hilgenfeld (eds.) Modern Methods of Drug Discovery. Basel - Boston – Berlin, 2003 (akceptējams izdevums) | ||||||||
| 3 | C.G. Wermuth (ed). The Practice of Medicinal Chemistry. Amsterdam, 2015 | ||||||||
