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Biostatistics

Study Course Description

Course Description Statuss:Approved
Course Description Version:4.00
Study Course Accepted:12.08.2022 10:59:25
Study Course Information
Course Code:SL_007LQF level:Level 7
Credit Points:2.00ECTS:3.00
Branch of Science:Mathematics; Theory of Probability and Mathematical StatisticsTarget Audience:Clinical Pharmacy
Study Course Supervisor
Course Supervisor:Vinita Cauce
Study Course Implementer
Structural Unit:Statistics Unit
The Head of Structural Unit:
Contacts:23 Kapselu street, 2nd floor, Riga, +371 67060897, statistikaatrsu[pnkts]lv, www.rsu.lv/statlab
Study Course Planning
Full-Time - Semester No.1
Lectures (count)0Lecture Length (academic hours)0Total Contact Hours of Lectures0
Classes (count)8Class Length (academic hours)3Total Contact Hours of Classes24
Total Contact Hours24
Study course description
Preliminary Knowledge:
Secondary school knowledge in mathematics and informatics.
Objective:
To provide students with the opportunity to acquire basic knowledge and skills in statistical data processing methods (descriptive statistics, inferential statistics methods for evaluating differences and analytical statistics), which are necessary for the development of scientific research work and the application of statistical indicators in their specialty.
Topic Layout (Full-Time)
No.TopicType of ImplementationNumberVenue
1Introduction to statistics, the role of statistics in research process. Data types, measure, data input, data preparation in MS Excel. Introduction to IBM SPSS.Classes1.00computer room
2Descriptive statistics for quantitative and qualitative data. Descriptive statistics of the Normal distribution. Creation of tables and diagrams, correct design.Classes1.00computer room
3Hypothesis testing. Parametric and nonparametric tests for quantitative data.Classes1.00computer room
4Hypothesis testing. Tests for qualitative data.Classes1.00computer room
5Correlation analysis in MS Excel and IBM SPSS.Classes1.00computer room
6Regression analysis. ROC curves.Classes0.50computer room
7Survival analysis.Classes0.50computer room
8Sample size estimation (including clinical trials). Analysis of scientific publications.Classes1.00computer room
9Students presentations.Classes1.00computer room
Assessment
Unaided Work:
1. Individual work with the literature – prepare to lectures accordingly to the plan. 2. Individual analysis of scientific publication. 3. Individual work – every student will receive a research data file (or student can use their own) with previously defined research tasks. Student will statistically process data to reach defined tasks using descriptive statistic, inferential statistic and/or analytical statistics methods. As well as to report obtained results in final paper, using defined formatting style and to present obtained results in the last lecture.
Assessment Criteria:
Participation in practical lectures. Scientific publication analysis, Recognise terminology used in statistics and basic methods used in different publications. To get a successful mark: 1. Multiple choice test about statistics – 50% 2. Scientific publication analysis – 30% 3. Individual work presentations – 20%
Final Examination (Full-Time):Exam (Written)
Final Examination (Part-Time):
Learning Outcomes
Knowledge:After successfully accomplished study course, students will have acquired knowledge to: Correctly interpret the main statistical tests; Describe measurement results using statistical parameters.
Skills:Will be able to define the hypotheses of basic statistical tests; Will be able to draw a normal distribution and calculate its main characteristic parameters; Will be able to calculate Pearson and Spearman correlation coefficients; Will be able to calculate and analyze the regression equation; Will be able to calculate independent and dependent sample t-tests; Will be able to perform Pearson's chi-square and Fisher's exact test; Will know how to use the processing program IBM SPSS for data processing and visualization; Will be able to assess the conformity of quantitative data with the existence of a normal distribution; Will be able to perform analysis of variance (ANOVA); Will be able to perform non-parametric tests - Mann-Whitney, Wilcoxon, Friedman and Kruskal-Wallis; Will know how to perform Kaplan-Meier survival analysis; Will be able to operate in the IBM SPSS computer program environment with data selection and perform the necessary calculations; Will be able to formulate the necessary statistical tests for analysis; analyze your own data; will be able to adequately process them and draw consequential and justified conclusions.
Competencies:As a result of learning the study course, students will be able to independently perform basic operations in the IBM SPSS environment, performing data processing, visualization and the necessary calculations.
Bibliography
No.Reference
Required Reading
1Teibe U. Bioloģiskā statistika. Rīga: LU Akadēmiskais apgāds, 2007, p 155. (akceptējams izdevums)
2Field A. Discovering Statistics using IBM SPSS Statistics. 5th edition, 2018.
Additional Reading
1Altman D. Practical Statistics for Medical Research. Chapman & Hall, 1999, pp. 612.