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ID-94 Channel-based biosensors to support a precision agriculture approach for improved bovine mastitis management

Project/agreement No.
ES RTD/2021/2
Project funding
205 000.00 EUR
Project manager
prof. Māra Pilmane, Beatriz Prieto-Simón
Project realization
01.04.2021. - 31.03.2024.

Aim

Analysis of milk samples (using milk cell sediments and smears), complex study of cytokines and antimicrobial peptides.

The identification of major cytokines and antimicrobial peptides indicating rapid changes in the initial, advanced inflammatory and suppression phases of inflammation. These are easy to detect and they serve to further establish a diagnostic-prognostic algorithm in bovine mastitis.

Description

The project has been approved for three years and will be based on new knowledge about host organism anti-inflammatory proteins and cytokines, as well as nucleic acids, that are identifiable as potential biomarkers of mastitis. Using the presence of these biomarkers in milk, a "liquid biopsy" approach to non-invasive and rapid sensor diagnostics of bovine mastitis will be used. The sensor technology will be an achievement in the diagnosis and prediction of mastitis, which will allow to start treatment before pathogen replication and manifestation of symptoms.

The development of channel-based biosensors will be carried out for on-the-spot milk analysis and the setting of parameters to be tested will provide a valuable advantage for the European dairy sector. It will justify early and rational use of antimicrobials in Europe, clarify the agricultural approach to disease control, infection prevention and appropriate antimicrobial management.

Partners

  • Rovira i Virgili University, Department of Electronic Engineering (Spain)
  • Seqomics Biotechnology Ltd (Hungary)
  • Research and Innovation Centre Pro-Akademia Natural Products Laboratory (Poland)

Project team

Prof. Beatriz Prieto-Simón
Project Manager
University Rovira i Virgili, ICREA (Spānija); Ramona Kahala stipendijas zinātniskā līdzstrādniece, ICRAD projekta vadītāja
Łukasz Gontar
Researcher
Pētniecības un inovāciju centrs Pro-Akademia, Polija
Gergely Maróti
Researcher
Seqomics Biotechnology Ltd. (Morahalom, Ungārija), līdzdibinātājs